SEPTIN2, septin 2, 4735

N. diseases: 44; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE Septin 2 (SEPT2) is a tumor-related gene belonging to the SEPT family that affects the cellular processes of hepatoma carcinoma cells, glioblastoma cells and mesangial cells and is highly expressed in breast cancer, biliary tract cancer and acute myeloid leukemia. 31402940 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE Repression of Septin9 and Septin2 suppresses tumor growth of human glioblastoma cells. 29724999 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 AlteredExpression group BEFREE Xenografts formation assay also showed that SEPT2 overexpression significantly facilitated the growth of tumor in vivo. 27155525 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 AlteredExpression group BEFREE We have recently shown a significant down-regulation of both SEPT2 and MLL in myeloid neoplasias with the MLL-SEPT2 fusion gene. 19748670 2010
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE We found a significant down-regulation of both SEPT2 and MLL in MLL-SEPT2 myeloid neoplasias. 19445675 2009