|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In this system, anti‑NRP‑1‑mAb located tTF to the tumor vascular endothelial cell surface and induced vascular embolization.
|
31432158 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Tumor xenografts model was used to evaluate the effect of NRP-1 on the tumor growth.
|
31114235 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
NRP-1 depletion suppressed tumor growth and liver metastasis and miR-141 mimics inhibited the growth of established tumors in mice.
|
31572065 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Anti-NRP-1 mAb could guide tTF to the surface of tumor vascular endothelial cells and lead to subsequent vascular embolization.
|
30807552 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The cellular transmembrane receptor Neuropilin-1(NRP-1) is overexpressed in tumour tissue and endothelial cells of tumour vessels, whereas it has limited expression in normal tissues.
|
30628471 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Widespread expression of NRP-1 in normal tissues may affect anti-NRP-1 antibody tumor uptake.
|
31692439 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The role of the hypoxia-Nrp-1 axis in the activation of M2-like tumor-associated macrophages in the tumor microenvironment of cervical cancer.
|
30362630 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In addition, tumor-penetrating CRGDK peptide-functionalized TPGS<sub>2k</sub> specifically bound to the Nrp-1 receptor to facilitate higher cell uptake of polymeric micelles by tumor cells.
|
29859925 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
New peptide MY1340 revert the inhibition effect of VEGF on dendritic cells differentiation and maturation via blocking VEGF-NRP-1 axis and inhibit tumor growth in vivo.
|
29730556 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Our study indicated that the novel transcript Nell-1-ΔE, but not full-length Nell-1, might be a candidate tumor suppressor factor for basic research and clinical practice.
|
29388706 |
2018 |
|
Neoplasms
|
0.100 |
PosttranslationalModification
|
group |
BEFREE |
In addition, we evaluated NELL1 methylation in cell lines derived from different urogenital tumors (prostate cancer, urothelial cancer and RCC).
|
30272321 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Dual integrin αvβ 3 and NRP-1-Targeting Paramagnetic Liposome for Tumor Early Detection in Magnetic Resonance Imaging.
|
30483904 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
A significant difference in tumor volume started to reveal between DXE-NRP-1 group and DXE-Control group.
|
26832839 |
2016 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In vivo, loss of NRP-1 attenuated tumor perfusion and size, accompanied by reduction in EndMT and fibrosis.
|
27542226 |
2016 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Thus, CpG ODN1826 can significantly inhibit tumor growth in a rat model, the mechanism of which may be related to inhibition of the expression of VEGF-C and NRP-1, which have an inhibitory effect on angiogenesis.
|
26345913 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Gene expression profiling by cDNA microarray revealed a set of up-regulated genes (hvegf-A165, cyclin b1, cdc2, egfr, mmp9, nrp-1, and kdr) in VEGF tumors compared with wild-type lung tissues.
|
25912305 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In an attempt to elucidate the relationship between biomarkers of tumor hypoxia, glycolysis and angiogenesis, we tested the hypothesis that intratumoral gene expression of the hypoxia response (hypoxia inducible factor [HIF1 alpha and 2 alpha]), glycolysis (lactate dehydrogenase A [LDHA]), glucose metabolism (glucose transporter-1 [Glut-1]) and genes involved in angiogenesis (i.e., VEGFA, VEGFR1-3, and neuropilin [NRP]1) are upregulated in metastatic colorectal cancer (mCRC) patients with high serum lactate dehydrogenase (LDH).
|
18086000 |
2007 |