NEFL, neurofilament light, 4747

N. diseases: 247; N. variants: 26
Disease: Down Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 Biomarker disease BEFREE Only NfL concentration in the group with DS showed a significant positive association with age. 30902060 2019
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 Biomarker disease BEFREE Plasma NF-L is associated with progressive neurodegeneration as well as with declines in cognitive and functional measures in adults with DS. 31156181 2019
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 Biomarker disease BEFREE NF-L is a biomarker for neurodegeneration in DS with potential for use in future clinical trials to prevent or delay dementia. 29631614 2018
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 Biomarker disease BEFREE Antibodies to dephospho-NF-M, NF-M, and NF-L were more common in DS samples than in controls. 19758141 2009