NEFL, neurofilament light, 4747

N. diseases: 247; N. variants: 26
Disease: Pick Disease of the Brain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		0.090 Biomarker disease BEFREE Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study. 31701893 2019
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		0.090 Biomarker disease BEFREE Levels of CSF NFL are associated with cognitive impairments in patients with Alzheimer disease and frontotemporal dementia. 30508027 2019
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		0.090 Biomarker disease BEFREE Neurofilament light chain as a blood biomarker to differentiate psychiatric disorders from behavioural variant frontotemporal dementia. 30953863 2019
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		0.090 Biomarker disease BEFREE Cerebrospinal fluid (CSF) neurofilament light chain protein (NfL) and Alzheimer's disease (AD) core biomarker levels have been evaluated in cohorts of patients with frontotemporal dementia spectrum (FTD), but the distribution of values across the different clinical syndromes and underlying proteinopathies, and the relative diagnostic accuracy appear discordant among studies. 30320576 2018
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		0.090 AlteredExpression disease BEFREE Cerebrospinal fluid NFL levels were quantified in nonprimarily neurodegenerative neurological and psychiatric diseases (n = 122), mild cognitive impairment (n = 48), Alzheimer's disease (n = 108), dementia with Lewy bodies/Parkinson's disease dementia (n = 53), vascular dementia (n = 46), frontotemporal dementia (n = 41), sporadic Creutzfeldt-Jakob disease (sCJD, n = 132), and genetic prion diseases (n = 182). 29391125 2018
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		0.090 Biomarker disease BEFREE To evaluate poly(GP), a dipeptide repeat protein, and neurofilament light chain (NfL) as biomarkers in presymptomatic <i>C9orf72</i> repeat expansion carriers and patients with <i>C9orf72-</i>associated frontotemporal dementia. 29761121 2018
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		0.090 Biomarker disease BEFREE Cerebrospinal fluid neurofilament light concentration in motor neuron disease and frontotemporal dementia predicts survival. 28631955 2017
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		0.090 Biomarker disease BEFREE Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia. 27581216 2016
CUI: C0236642
Disease: Pick Disease of the Brain
Pick Disease of the Brain 		0.090 AlteredExpression disease BEFREE In DS brain betaIII, NF-H and NF-M, in AD brain NF-M and NF-H and in PD brain NF-L, NF-M and NF-H were significantly reduced. 15068247 2003