Dental caries
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.
|
31235808 |
2019 |
Uric acid measurement (procedure)
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.
|
31578528 |
2019 |
Red cell distribution width determination
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Finding of Mean Corpuscular Hemoglobin
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
RDW - Red blood cell distribution width result
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Blood Protein Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Co-regulatory networks of human serum proteins link genetics to disease.
|
30072576 |
2018 |
Hydrocephalus
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Here, we reveal that loss of the netrin/RGM receptor, Neogenin, leads to severe hydrocephalus.
|
28700939 |
2017 |
Leukemia, Myelocytic, Acute
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A case of childhood acute myeloid leukemia AML (M5) with a neocentric chromosome neo(1)(qter-->q23 approximately 24::q23 approximately 24-->q43-->neo-->q43-->qter) and tetrasomy of chromosomes 8 and 21.
|
19665076 |
2009 |
Adult Acute Myeloblastic Leukemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A case of childhood acute myeloid leukemia AML (M5) with a neocentric chromosome neo(1)(qter-->q23 approximately 24::q23 approximately 24-->q43-->neo-->q43-->qter) and tetrasomy of chromosomes 8 and 21.
|
19665076 |
2009 |
Childhood Acute Myeloid Leukemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A case of childhood acute myeloid leukemia AML (M5) with a neocentric chromosome neo(1)(qter-->q23 approximately 24::q23 approximately 24-->q43-->neo-->q43-->qter) and tetrasomy of chromosomes 8 and 21.
|
19665076 |
2009 |
Iron Overload
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Livers of neogenin mutant mice exhibit iron overload, low levels of hepcidin, and reduced BMP signaling.
|
20065295 |
2010 |
Hereditary hemochromatosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In addition, the HJV G320V mutant implicated in Type 2A HH did not co-immunoprecipitate with neogenin.
|
16103117 |
2005 |
Autism Spectrum Disorders
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We identify genetic changes in both alleles of NEO1 in two individuals from a cohort of 66 Han Chinese patients with ASD.
|
26518331 |
2016 |
Acute monocytic/monoblastic leukemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Described here is the case of a 2(1/2)-year-old girl with AML-M5 and 51 chromosomes characterized by double tetrasomy of chromosomes 8 and 21 and also a neocentric derivative chromosome neo(1)(qter-->q23 approximately 24::q23 approximately 24-->q43-->neo-->q43-->qter).
|
19665076 |
2009 |
Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Neogenin is closely related to the human tumor suppressor gene deleted in colorectal cancer and plays a role in mammary morphogenesis.
|
25416629 |
2014 |
Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
The present study demonstrates that neogenin may be a tumor suppressor in breast cancer.
|
25998984 |
2015 |
Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
The enzymes deplete cells of tumour suppressors such as deleted in colorectal cancer (DCC) and neogenin, so their potential presence in the food chain might represent an important link between diet and cancer.
|
28238104 |
2017 |
Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Moreover, our recent studies demonstrate that netrin-1/neogenin interactions augment CD4+ T cell chemokinesis and elicit pro-inflammatory responses, suggesting that netrin-1 plays a key role in modulating the function of a tumor and its surrounding cells in the tumor microenvironment.
|
30532711 |
2018 |
Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
NEO1 and DCC are also tumor suppressors that can inhibit metastasis by acting as dependence receptors.
|
30858446 |
2019 |
Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
A second new hypothesis is based on evidence that serine proteases can deplete cells of the tumour suppressors Deleted in Colorectal Cancer (DCC) and neogenin.
|
29526577 |
2018 |
Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Kaplan-Meier plot and Cox proportional hazards modelling showed that over-expressive neogenin could prolong the tumor latency (n = 69, p<0.001, 1187.6 ± 162.6 days versus 687.4 ± 254.2 days) and restrain high-grade glioma development (n = 69, p<0.01, HR: 0.264, 95% CI: 0.102 to 0.687).
|
22666451 |
2012 |
Neoplasms
|
0.090 |
Biomarker
|
group |
BEFREE |
Expression of the tumour suppressor Deleted in Colorectal Cancer (DCC) and the related protein neogenin is reduced by the mammalian serine protease chymotrypsin or the bacterial serine protease subtilisin, with increased cell migration.
|
30403907 |
2019 |
Malignant Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
The enzymes deplete cells of tumour suppressors such as deleted in colorectal cancer (DCC) and neogenin, so their potential presence in the food chain might represent an important link between diet and cancer.
|
28238104 |
2017 |
Malignant Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Neogenin has been documented as playing an important role in cancer development.
|
25998984 |
2015 |