NF1, neurofibromin 1, 4763

N. diseases: 380; N. variants: 935
Disease: leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023418
Disease: leukemia
leukemia 		0.340 AlteredExpression disease LHGDN Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis. 18172006 2008
CUI: C0023418
Disease: leukemia
leukemia 		0.340 GeneticVariation disease BEFREE First, evidence of loss of heterozygosity (LOH) of the NF1 gene region was investigated, and, second, a screen for the presence of sequence alterations was conducted on a large panel of DNA derived from matched blood/tumour pairs. 10633134 2000
CUI: C0023418
Disease: leukemia
leukemia 		0.340 GeneticVariation disease BEFREE A loss of heterozygosity of NF1 gene may contribute to the progression of leukemia in NF-1 patients. 9713168 1998
CUI: C0023418
Disease: leukemia
leukemia 		0.340 GeneticVariation disease BEFREE Additional molecular genetic analysis is necessary to determine if the NF1 gene is inactivated by somatic mutation in these secondary leukemias. 9083167 1997
CUI: C0023418
Disease: leukemia
leukemia 		0.340 CausalMutation disease CGI
CUI: C0023418
Disease: leukemia
leukemia 		0.340 GenomicAlterations disease CGI