NF2, neurofibromin 2, 4771

N. diseases: 312; N. variants: 54
Disease: Benign Meningioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0281784
Disease: Benign Meningioma
Benign Meningioma 		0.330 PosttranslationalModification disease BEFREE The role and regulatory mechanism of IL-1β on the methylation of the NF2 gene in benign meningiomas and leptomeninges. 26840621 2016
CUI: C0281784
Disease: Benign Meningioma
Benign Meningioma 		0.330 Biomarker disease CTD_human Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. 23334667 2013
CUI: C0281784
Disease: Benign Meningioma
Benign Meningioma 		0.330 GeneticVariation disease BEFREE Results showed a high frequency of NF2 gene mutations (40%), increased 22q LOH as aggressiveness increased, frequent losses and gains by MLPA in benign meningiomas, and gene expression silencing by hypermethylation. 19148485 2009
CUI: C0281784
Disease: Benign Meningioma
Benign Meningioma 		0.330 Biomarker disease BEFREE The neurofibromatosis Type 2 (NF2) gene is the only tumor suppressor gene that has been clearly implicated in the development of benign meningiomas. 11147878 2001