Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.060 AlteredExpression group BEFREE We previously described NFE2 mutations in patients with myeloproliferative neoplasms and demonstrated that expression of mutant NFE2 in mice causes a myeloproliferative phenotype. 30755419 2019
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.060 AlteredExpression group BEFREE Epigenetic regulation of NFE2 overexpression in myeloproliferative neoplasms. 29519804 2018
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.060 AlteredExpression group BEFREE Recently, an increased in NF-E2 activity has been implicated in myeloproliferative neoplasms. 28648895 2017
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.060 Biomarker group BEFREE Overexpression of transcription factors runt-related transcription factor 1 (RUNX1) and nuclear factor, erythroid-derived 2 (NF-E2) was reported in granulocytes of patients with polycythemia vera and other myeloproliferative neoplasms (MPNs). 24297870 2014
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.060 GeneticVariation group BEFREE The HDAC inhibitor Givinostat modulates the hematopoietic transcription factors NFE2 and C-MYB in JAK2(V617F) myeloproliferative neoplasm cells. 22579713 2012
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.060 AlteredExpression group BEFREE AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2. 20339092 2010