NFE2, nuclear factor, erythroid 2, 4778

N. diseases: 57; N. variants: 3
Disease: Thrombocytosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0836924
Disease: Thrombocytosis
Thrombocytosis 		0.030 AlteredExpression disease BEFREE Sustained overexpression of NF-E2 in this model induced myeloid expansion with anemia, leukocytosis and thrombocytosis. 23932394 2014
CUI: C0836924
Disease: Thrombocytosis
Thrombocytosis 		0.030 GeneticVariation disease BEFREE These result in truncated NF-E2 proteins that enhance wild-type (WT) NF-E2 function and cause erythrocytosis and thrombocytosis in a murine model. 23589569 2013
CUI: C0836924
Disease: Thrombocytosis
Thrombocytosis 		0.030 AlteredExpression disease BEFREE In this model, the level of NF-E2 overexpression determines both the severity of erythrocytosis and the concurrent presence or absence of thrombocytosis. 15801966 2005