Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0341106
Disease: Eosinophilic esophagitis
Eosinophilic esophagitis
0.030 Biomarker disease BEFREE The main causes of refractory heartburn include: poor compliance; inadequate proton-pump inhibitors dosage; incorrect diagnosis; comorbidities; genotypic differences; residual gastroesophageal reflux; eosinophilic esophagitis and others. 29352757 2018
CUI: C0341106
Disease: Eosinophilic esophagitis
Eosinophilic esophagitis
0.030 GeneticVariation disease BEFREE The use of proton-pump inhibitors (PPI) is being suggested as a potential regimen to treat EoE, based on evolving understanding of PPI-responsive esophageal eosinophilia (PPI-REE). 29753831 2018
CUI: C0341106
Disease: Eosinophilic esophagitis
Eosinophilic esophagitis
0.030 Biomarker disease BEFREE In this review, we will summarize recent advances in our understanding of EoE and discuss the mechanisms of action of current treatment options, with emphasis on the role of the esophageal epithelial barrier and the effects of proton-pump inhibitors in the management of patients with EoE. 28644315 2017