Diabetes Mellitus, Non-Insulin-Dependent
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
Type 2 diabetes is associated with increased expression of APOE, BAX, MMP1, NFKB1, PDGFB, SPP1, and TGFB2.
|
23337395 |
2014 |
Adenocarcinoma
|
0.370 |
Biomarker
|
group |
CTD_human |
Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats.
|
19028472 |
2009 |
Adenocarcinoma
|
0.370 |
AlteredExpression
|
group |
LHGDN |
Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinoma.
|
18715846 |
2008 |
Adenocarcinoma
|
0.370 |
Biomarker
|
group |
LHGDN |
Use of bioluminescent imaging to investigate the role of nuclear factor-kappaBeta in experimental non-small cell lung cancer metastasis.
|
18008176 |
2008 |
Adenocarcinoma
|
0.370 |
AlteredExpression
|
group |
LHGDN |
EGF-R is expressed and AP-1 and NF-kappaB are activated in stromal myofibroblasts surrounding colon adenocarcinomas paralleling expression of COX-2 and VEGF.
|
18032824 |
2007 |
Adenocarcinoma
|
0.370 |
GeneticVariation
|
group |
LHGDN |
Clinical biology of esophageal adenocarcinoma after surgery is influenced by nuclear factor-kappaB expression.
|
17548685 |
2007 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.370 |
Biomarker
|
disease |
CTD_human |
Molecular epidemiologic evidence for diabetogenic effects of dioxin exposure in U.S. Air force veterans of the Vietnam war.
|
17107852 |
2006 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
We examined the CA repeat polymorphism of the NFKB1 gene (encoding for NFkappaB) and A/G point variation in the 3'UTR region of the nuclear factor kappa B inhibitor alpha (NFKBIA) gene (encoding for IkappaB) in Czech and German patients with type 2 diabetes.
|
17002901 |
2006 |
Adenocarcinoma
|
0.370 |
Biomarker
|
group |
LHGDN |
Expression of nuclear factor-kappa B and I kappa B alpha proteins in prostatic adenocarcinomas: correlation of nuclear factor-kappa B immunoreactivity with disease recurrence.
|
15073126 |
2004 |
Adenocarcinoma
|
0.370 |
AlteredExpression
|
group |
LHGDN |
NF-kappaB-dependent MnSOD expression protects adenocarcinoma cells from TNF-alpha-induced apoptosis.
|
12032830 |
2002 |
Alcoholic Intoxication, Chronic
|
0.350 |
GeneticVariation
|
disease |
BEFREE |
The present study analyzed potential relationships between alcoholism or alcoholic liver disease (ALD) and IL12B 2124 G>T (rs1368439), IL16 5000 C>T (rs1131445), IL1R1 3114 C>T (rs3917328), and NFKB1 3400 A>G (rs4648143) polymorphisms.
|
29566963 |
2018 |
Alcoholic Intoxication, Chronic
|
0.350 |
Biomarker
|
disease |
PSYGENET |
Transcriptional control of maladaptive and protective responses in alcoholics: a role of the NF-κB system.
|
21195164 |
2011 |
Alcoholic Intoxication, Chronic
|
0.350 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms of human NF-κB1 and other innate immune genes contribute to genetic risk for alcoholism.
|
21402143 |
2011 |
Alcoholic Intoxication, Chronic
|
0.350 |
GeneticVariation
|
disease |
BEFREE |
We found an association between the presence of the deletion allele in NFKB1 polymorphism and ALC in patients with alcohol dependence.
|
19673747 |
2009 |
Alcoholic Intoxication, Chronic
|
0.350 |
Biomarker
|
disease |
PSYGENET |
We found an association between the presence of the deletion allele in NFKB1 polymorphism and ALC in patients with alcohol dependence.
|
19673747 |
2009 |
Alcoholic Intoxication, Chronic
|
0.350 |
GeneticVariation
|
disease |
LHGDN |
NF-kappaB regulates many genes relevant to brain function, and its actions can be potentiated by ethanol; thus, NFKB1 is an excellent candidate gene for alcoholism.
|
18079108 |
2008 |
Alcoholic Intoxication, Chronic
|
0.350 |
Biomarker
|
disease |
PSYGENET |
NF-kappaB regulates many genes relevant to brain function, and its actions can be potentiated by ethanol; thus, NFKB1 is an excellent candidate gene for alcoholism.
|
18079108 |
2008 |
Alcoholic Intoxication, Chronic
|
0.350 |
Biomarker
|
disease |
BEFREE |
NF-kappaB regulates many genes relevant to brain function, and its actions can be potentiated by ethanol; thus, NFKB1 is an excellent candidate gene for alcoholism.
|
18079108 |
2008 |
Alcoholic Intoxication, Chronic
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
Alterations in expression of p50 homodimer/NF-kappaB regulated genes may contribute to neuroplastic adaptation underlying alcoholism.
|
17895971 |
2007 |
Alcoholic Intoxication, Chronic
|
0.350 |
Biomarker
|
disease |
PSYGENET |
Alterations in expression of p50 homodimer/NF-kappaB regulated genes may contribute to neuroplastic adaptation underlying alcoholism.
|
17895971 |
2007 |
Liver diseases
|
0.340 |
Biomarker
|
group |
BEFREE |
Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases.
|
30070632 |
2018 |
Liver diseases
|
0.340 |
AlteredExpression
|
group |
BEFREE |
However, M120 V mutation may utilize a different pathway in liver disease progression that involves high expression of NF-κB subunit, p50.
|
29652648 |
2018 |
Liver diseases
|
0.340 |
GeneticVariation
|
group |
BEFREE |
In this case-control study, 559 subjects (343 patients with HCV infection including 237 mild chronic hepatitis patients and 106 patients with Advanced Liver Disease (AdLD), 78 individuals who naturally cleared HCV and 138 healthy subjects) were genotyped for the NFκB1 and NFκBIA SNPs using PCR-RFLP.
|
26827631 |
2016 |
Liver diseases
|
0.340 |
GeneticVariation
|
group |
BEFREE |
A total of 258 male alcoholics (161 without liver disease and 97 with ALC) and 101 healthy controls were genotyped for the -94ins/delATTG NFKB1, 3'-UTR+126G>A NFKBIA, and 34C>G PPARG2 polymorphisms.
|
19673747 |
2009 |
Liver diseases
|
0.340 |
Therapeutic
|
group |
CTD_human |
Taken together these data indicate that the p50 NF-kappaB subunit plays a critical protective role in the injured liver by limiting the expression of TNF-alpha and its recruitment of inflammatory cells.
|
15743782 |
2005 |