White Blood Cell Count procedure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Mutations in gene locations of CDKN2B-AS1 (Rs2383206), HDAC9 (Rs11984041), NINJ2 (Rs12425791), NAA25 (Rs17696736) are not risk factors for ischemic stroke in childhood.
|
30656483 |
2019 |
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Consequently, the present case-control study supports the role of NINJ2 as a risk locus for ischemic stroke in Iranian population.
|
31372770 |
2019 |
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Thus, we carried out a meta-analysis to identify the association between nerve injury-induced protein 2 (NINJ2) gene polymorphisms (rs11833579 and rs12425791) and the risk of IS.
|
31258083 |
2019 |
Platelet Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
|
29403010 |
2018 |
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
However, the underlying mechanisms of NINJ2 in ischemic stroke or atherosclerosis are still unknown.
|
28431986 |
2017 |
Platelet Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Lymphocyte Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Monocyte count procedure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Monocyte count result
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Platelet Component Distribution Width Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Common and rare variants in the NINJ2 region were nominally associated with incident ischemic stroke among a subset of CHARGE participants.
|
24959832 |
2014 |
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A GWAS found that the single-nucleotide polymorphism rs11833579 near the NINJ2 gene on chromosome 12p13 was associated with an increased risk of ischemic stroke in Caucasians in 2009.
|
25096477 |
2014 |
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Significant allelic association was identified between NINJ2 gene rs11833579 (P = 0.008), protein kinase C η gene rs2230501 (P = 0.039) and IS.
|
24664524 |
2014 |
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association between 12p13 SNPs rs11833579/rs12425791 near NINJ2 gene and ischemic stroke in East Asian population: evidence from a meta-analysis.
|
22297388 |
2012 |
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In 2009, a GWAS has confirmed that rs11833579 and rs12425791 near the NINJ2 gene could increase the stroke and ischemic stroke (IS) risk.
|
22795341 |
2012 |
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
No evidence for association of 12p13 SNPs rs11833579 and rs12425791 within NINJ2 gene with ischemic stroke in Chinese Han population.
|
21376321 |
2011 |
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Therefore, we report a new genetic variant, rs10849373, located in the first intron of the NINJ2 gene, conferring risk of ischemic stroke in Chinese Han subjects.
|
21722921 |
2011 |
Cerebrovascular accident
|
0.080 |
GeneticVariation
|
group |
BEFREE |
Among the acknowledged risk factors of stroke are the single nucleotide polymorphisms (SNPs) near Ninjurin 2 (NINJ2) gene which encodes a surface adhesion protein.
|
31372770 |
2019 |
Cerebrovascular accident
|
0.080 |
GeneticVariation
|
group |
BEFREE |
Previous genetic studies suggested that variants in NINJ2 (encode ninjurin2) confer risk to ischemic stroke or large artery atherosclerotic stroke.
|
28431986 |
2017 |
Cerebrovascular accident
|
0.080 |
GeneticVariation
|
group |
BEFREE |
Other loci associated with stroke in previous studies, including NINJ2, were not confirmed.
|
26708676 |
2016 |
Cerebrovascular accident
|
0.080 |
GeneticVariation
|
group |
BEFREE |
In 2009, a genome-wide association study (GWAS) identified two variants (rs12425791 and rs11833579) near NINJ2 gene that confer susceptibility to stroke in Caucasian populations.
|
26312640 |
2016 |
Cerebrovascular accident
|
0.080 |
GeneticVariation
|
group |
BEFREE |
Further validation of the functionality of the NINJ2 rs3809263 G > A polymorphism and its association with risk of LAA stroke in other ethnic populations is warranted.
|
26687183 |
2016 |
Cerebrovascular accident
|
0.080 |
GeneticVariation
|
group |
BEFREE |
In 2009, a GWAS has confirmed that rs11833579 and rs12425791 near the NINJ2 gene could increase the stroke and ischemic stroke (IS) risk.
|
22795341 |
2012 |
Cerebrovascular accident
|
0.080 |
GeneticVariation
|
group |
BEFREE |
Recent genome-wide association (GWA) studies have identified two intergenic single nucleotide polymorphisms (SNPs) (rs11833579 and rs12425791) on chromosome 12p13 and within 11 kb of the NINJ2 gene that were significantly associated with stroke in Caucasians.
|
21376321 |
2011 |