NODAL, nodal growth differentiation factor, 4838

N. diseases: 89; N. variants: 12
Disease: Multiple congenital anomalies ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0000772
Disease: Multiple congenital anomalies
Multiple congenital anomalies 		0.100 GeneticVariation group CLINVAR Non-cardiac issues in patients with heterotaxy syndrome. 25298693 2014
CUI: C0000772
Disease: Multiple congenital anomalies
Multiple congenital anomalies 		0.100 GeneticVariation group CLINVAR Novel mutations of NODAL gene in Chinese patients with congenital heart disease. 22352765 2012
CUI: C0000772
Disease: Multiple congenital anomalies
Multiple congenital anomalies 		0.100 GeneticVariation group CLINVAR Familial transposition of the great arteries caused by multiple mutations in laterality genes. 19933292 2010
CUI: C0000772
Disease: Multiple congenital anomalies
Multiple congenital anomalies 		0.100 GeneticVariation group CLINVAR Cumulative ligand activity of NODAL mutations and modifiers are linked to human heart defects and holoprosencephaly. 19553149 2009
CUI: C0000772
Disease: Multiple congenital anomalies
Multiple congenital anomalies 		0.100 GeneticVariation group CLINVAR Identification and functional characterization of NODAL rare variants in heterotaxy and isolated cardiovascular malformations. 19064609 2009
CUI: C0000772
Disease: Multiple congenital anomalies
Multiple congenital anomalies 		0.100 GeneticVariation group CLINVAR Heterotaxia syndromes and their abdominal manifestations. 16721152 2006
CUI: C0000772
Disease: Multiple congenital anomalies
Multiple congenital anomalies 		0.100 GeneticVariation group CLINVAR Nodal signaling in early vertebrate embryos: themes and variations. 11709181 2001
CUI: C0000772
Disease: Multiple congenital anomalies
Multiple congenital anomalies 		0.100 GeneticVariation group CLINVAR X-linked situs abnormalities result from mutations in ZIC3. 9354794 1997
CUI: C0000772
Disease: Multiple congenital anomalies
Multiple congenital anomalies 		0.100 GeneticVariation group CLINVAR Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. 8610013 1996
CUI: C0000772
Disease: Multiple congenital anomalies
Multiple congenital anomalies 		0.100 GeneticVariation group CLINVAR Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. 8429908 1993