NOTCH1, notch receptor 1, 4851

N. diseases: 693; N. variants: 64
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 AlteredExpression group BEFREE The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L. 29662198 2018
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 AlteredExpression group BEFREE Visfatin and Notch1 were expressed at higher levels in breast tumors than in matched control tissues. 24970818 2014
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 Biomarker group CTD_human NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications. 21679465 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 Biomarker group CTD_human Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation. 21036696 2010
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 AlteredExpression group BEFREE Furthermore, KLF4 and Notch1 expression are correlated in primary human breast tumors (N = 89; Pearson analysis, r > 0.5, p < 0.0001). 19717984 2009
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 AlteredExpression group LHGDN A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis. 18559519 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 Biomarker group LHGDN Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis. 18593928 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 Biomarker group LHGDN Effects of recombinant erythropoietin on breast cancer-initiating cells. 18084619 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 AlteredExpression group LHGDN A study on Notch signaling in human breast cancer. 17822320 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 Biomarker group LHGDN Notch-1 expression was low in grade 1 tumours and increased in poorly-differentiated tumours, whereas, Notch-2 expression was high in well-differentiated tumours and reduced in breast tumours with poor differentiation. 15492845 2004
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.380 AlteredExpression group BEFREE Notch-1 expression was low in grade 1 tumours and increased in poorly-differentiated tumours, whereas, Notch-2 expression was high in well-differentiated tumours and reduced in breast tumours with poor differentiation. 15492845 2004