NOTCH1, notch receptor 1, 4851

N. diseases: 693; N. variants: 64
Disease: Tumor Angiogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.030 Biomarker phenotype BEFREE EGFR is involved in the tumor angiogenesis of HNSCC via the HIF-1α and Notch1 pathways. 25723392 2015
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.030 Biomarker phenotype BEFREE Its inactivation led to NOTCH1 activation, upregulation of NOTCH1 target genes (by 2.6-fold), and promotion of tumor angiogenesis and resulted in tumor shrinkage upon NOTCH1 inhibition (by fivefold). 24838835 2014
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.030 Biomarker phenotype BEFREE Notch-1 may play an important role in regulating the proliferation of GCSCs; XTSJ decoction could attenuate tumor angiogenesis, at least partially, by inhibiting Notch-1. 25278704 2014