Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.
|
30054458 |
2018 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
Biomarker
|
disease |
BEFREE |
Altered expression of WFS1 and NOTCH2 genes may play a role in pathogenesis and development of DN in patients with T2DM.
|
29626590 |
2018 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
GWASCAT |
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.
|
28869590 |
2017 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
AlteredExpression
|
disease |
BEFREE |
Altered expression of Notch2 and ABCC8 genes may play a role in the pathogenesis of T2DM.
|
28794851 |
2017 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
|
23300278 |
2013 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
BEFREE |
These findings suggest that genetic variation in NOTCH2 increased susceptibility to T2DM among people exposed to inorganic arsenic.
|
23967108 |
2013 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
BEFREE |
To examine the association of type 2 diabetes susceptibility loci and visceral fat accumulation, we genotyped 1279 Japanese subjects (556 men and 723 women), who underwent computed tomography for measurements of visceral fat area (VFA) and subcutaneous fat area (SFA) for the following single-nucleotide polymorphisms (SNPs): NOTCH2 rs10923931, THADA rs7578597, PPARG rs1801282, ADAMTS9 rs4607103, IGF2BP2 rs1470579, VEGFA rs9472138, JAZF1 rs864745, CDKN2A/CDKN2B rs564398 and rs10811661, HHEX rs1111875 and rs5015480, TCF7L2 rs7901695, KCNQ1 rs2237892, KCNJ11 rs5215 and rs5219, EXT2 rs1113132, rs11037909, and rs3740878, MTNR1B rs10830963, DCD rs1153188, TSPAN8/LGR5 rs7961581, and FTO rs8050136 and rs9939609.
|
22377712 |
2012 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
|
21647700 |
2011 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
Biomarker
|
disease |
BEFREE |
Notably five of them, IGF2BP2, KCNJ11, NOTCH2, TCF7L2 and TSPAN8, have subsequently been shown to be associated with T2DM in different populations.
|
20043853 |
2009 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
GWASDB |
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
|
18372903 |
2008 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
BEFREE |
We evaluated the impact on diabetes-related intermediary traits of common novel type 2 diabetes-associated variants in the JAZF1 (rs864745), CDC123/CAMK1D (rs12779790), TSPAN8 (rs7961581), THADA (rs7578597), ADAMTS9 (rs4607103), and NOTCH2 (rs10923931) loci, which were recently identified by meta-analysis of genome-wide association data.
|
18567820 |
2008 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
Biomarker
|
disease |
CTD_human |
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
|
18372903 |
2008 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
|
18372903 |
2008 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.460 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.
|
17463246 |
2007 |