|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
BNP, which is synthesized in the cardiac ventricles and correlates with LV pressure, amount of dyspnea, and the state of neurohormonal modulation, makes this peptide the first potential "white count" for heart failure.
|
11715177 |
2001 |
|
Congestive heart failure
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The body weight, heart weight index (HWI), heart weight/tibia length ratio (HW/TL), and serum BNP level were investigated to assess the effect of LGZG on HF.
|
31829159 |
2019 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
The measurements of plasma natriuretic peptides (NT-proBNP, proBNP and BNP) are used to diagnose heart failure but these are expensive to produce.
|
24101238 |
2014 |
|
Congestive heart failure
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Baseline rSO2 was lower in patients with heart failure (45.2±8.3 % vs. 54.1±7.8 %, p=0.006) and was significantly linked to higher red cell distribution width (RDW) (r=-0.53, p?0.001) and higher BNP level (r=-0.45, p=0.01).
|
31177793 |
2019 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
The Sesn2 concentrations were positively correlated with N-terminal B-type natriuretic peptide (NT-pro BNP) but negatively correlated with left ventricular ejection fraction (LVEF) in CHF patients.
|
31059702 |
2019 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
CTD_human |
Brain natriuretic peptide is a predictor of anthracycline-induced cardiotoxicity.
|
11279304 |
2000 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Assessment of GVRs revealed that the correctly trained model highlighted conventional radiographic features of CHF as reasons for an elevated BNP prediction more frequently than the overfitted model, including cardiomegaly (153 [76.5%] of 200 vs 64 [32%] of 200, respectively; P < .001) and pleural effusions (47 [23.5%] of 200 vs 16 [8%] of 200, respectively; P = .003).
|
30398431 |
2019 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Because NE and BNP are considered as neurohormones indicating heart failure progression, we also determined the levels of plasma NE and BNP-45 besides cardiac function.
|
29879885 |
2018 |
|
Congestive heart failure
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The comparison of prognosis⁻predictivity of a single measurement of plasma NT-pro BNP in different follow-up periods in acute HF patients has been less studied.
|
30871208 |
2019 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Baseline BNP; subsequent hospitalization for heart failure or death.
|
28768311 |
2017 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
CTD_human |
The effects of atorvastatin (10 mg) on systemic inflammation in heart failure.
|
16360360 |
2005 |
|
Congestive heart failure
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Echocardiography and the expression of BNP showed that rivaroxaban attenuated heart failure.
|
30867376 |
2019 |
|
Congestive heart failure
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Over time, FKBP12.6 over-expression reduced the molecular signature of left ventricular hypertrophy (LVH) and the transition to HF (BNP and β-MHC mRNAs) and attenuated Cn/NFAT activation in TAC-males only.
|
22007848 |
2011 |
|
Congestive heart failure
|
0.600 |
Therapeutic
|
disease |
CTD_human |
The prognostic value of big endothelin-1 in more than 2,300 patients with heart failure enrolled in the Valsartan Heart Failure Trial (Val-HeFT).
|
16762801 |
2006 |
|
Congestive heart failure
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Congestive heart failure is accompanied by increased cardiac brain natriuretic peptide (BNP) gene expression with elevated plasma concentrations of BNP and its precursor, proBNP.
|
12709407 |
2003 |
|
Congestive heart failure
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Patients with heart failure and CSA-CSR ± OSA have higher RRs but similar MV under ASV-therapy than patients with CSA and normal BNP.
|
29940592 |
2019 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
However, the combination of miRNAs and BNP could increase the accuracy of detecting of heart failure.
|
28562533 |
2017 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
RGD |
Increased plasma levels and blunted effects of brain natriuretic peptide in rats with congestive heart failure.
|
1831369 |
1991 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
CTD_human |
[B-type natriuretic peptide (BNP) levels and the effects of carvedilol on BNP levels in juvenile rats with right heart failure].
|
19650993 |
2009 |
|
Congestive heart failure
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Conclusions Analytical performances of the BNP and PBNP ADVIA methods are well in accordance with the quality specifications required by international guidelines for diagnosis and follow-up of patients with HF.
|
30412461 |
2019 |
|
Congestive heart failure
|
0.600 |
Therapeutic
|
disease |
CTD_human |
[B-type natriuretic peptide (BNP) levels and the effects of carvedilol on BNP levels in juvenile rats with right heart failure].
|
19650993 |
2009 |
|
Congestive heart failure
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Accompanying these effects, tadalafil treatment normalized BNP mRNA and prevented development of subjective signs of HF.
|
31043634 |
2019 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
In BIO14.6 and BIO53.58 strains at this age, ventricular BNP and ANP gene expressions are augmented, and the plasma BNP concentration is elevated to 136 and 108 fmol/ml, respectively, three times greater than the elevated plasma ANP concentration, which well mimics changes of the plasma BNP and ANP concentrations in human heart failure.
|
8083346 |
1994 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
BEFREE |
Currently, N-terminal pro-B-type natriuretic peptide (NT-proBNP) and its physiologically active counterpart, BNP, are most frequently used as biomarkers for diagnosis, prognosis, and disease monitoring of heart failure (HF).
|
28062629 |
2017 |
|
Congestive heart failure
|
0.600 |
Biomarker
|
disease |
CTD_human |
Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure.
|
24535859 |
2014 |