NPY1R, neuropeptide Y receptor Y1, 4886

N. diseases: 59; N. variants: 5
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.500 Biomarker disease CTD_human Several genes and transcripts involved in lipolysis were down-regulated, such as AKAP1, PRKAR2B, Gi and CIDEA, whereas NPY1R and CES1 were up-regulated, when comparing obese to lean subjects. 20975297 2010
CUI: C0028754
Disease: Obesity
Obesity 		0.500 Biomarker disease RGD Difference of NPY and its receptor gene expressions between obesity and obesity-resistant rats in response to high-fat diet. 17447163 2007
CUI: C0028754
Disease: Obesity
Obesity 		0.500 Biomarker disease MGD Behavioural, neural and cardiovascular adaptations in mice lacking the NPY Y1 receptor. 15652259 2005
CUI: C0028754
Disease: Obesity
Obesity 		0.500 Biomarker disease MGD Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression. 14525913 2004
CUI: C0028754
Disease: Obesity
Obesity 		0.500 Biomarker disease MGD Voluntary alcohol consumption is controlled via the neuropeptide Y Y1 receptor. 11826154 2002
CUI: C0028754
Disease: Obesity
Obesity 		0.500 Biomarker disease MGD Increased insulin concentrations and glucose storage in neuropeptide Y Y1 receptor-deficient mice. 11287097 2001