NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3665593
Disease: Melanocytic nevus of skin
Melanocytic nevus of skin
0.040 GeneticVariation disease BEFREE Our results suggest that mutations in the BRAF gene and to some extent in the N-ras gene represent early somatic events that occur in melanocytic nevi. 15009715 2004
CUI: C3665593
Disease: Melanocytic nevus of skin
Melanocytic nevus of skin
0.040 GeneticVariation disease BEFREE BRAF and NRAS mutations in melanoma and melanocytic nevi. 16845322 2006
CUI: C3665593
Disease: Melanocytic nevus of skin
Melanocytic nevus of skin
0.040 GeneticVariation disease BEFREE It is not known whether melanocytic nevi that are found in association with a melanoma are more likely to carry BRAF or NRAS mutations than uninvolved nevi. 23861977 2013
CUI: C3665593
Disease: Melanocytic nevus of skin
Melanocytic nevus of skin
0.040 GeneticVariation disease BEFREE These findings document that common conjunctival melanocytic nevi have mutually exclusive mutations in BRAF and NRAS. 29332123 2018