NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome
0.780 CausalMutation disease CLINVAR Repressible transgenic model of NRAS oncogene-driven mast cell disease in the mouse. 15831708 2005
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome
0.780 CausalMutation disease CLINVAR Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia. 14982869 2004
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome
0.780 CausalMutation disease CLINVAR Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis. 15046639 2004
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome
0.780 CausalMutation disease CLINVAR Juvenile myelomonocytic leukemia and Noonan syndrome. 10598665 2000
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome
0.780 Biomarker disease GENOMICS_ENGLAND