NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.480 GeneticVariation disease BEFREE Here, we investigated the reliability of IHC to identify N-RAS Q61R mutated thyroid neoplasia. 28064410 2017
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.480 Biomarker disease BEFREE TERT, BRAF, and NRAS in Primary Thyroid Cancer and Metastatic Disease. 28323937 2017
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.480 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.480 GeneticVariation disease BEFREE We performed IHC for NRAS(Q61R) and direct sequencing for NRAS codon 61 in 4 thyroid cancer-derived cell lines and 98 follicular-patterned thyroid tumors that included 22 follicular thyroid adenomas (FTAs), 35 follicular thyroid carcinomas (FTCs), and 41 cases of nodular hyperplasia (NH). 26980032 2016
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.480 Biomarker disease BEFREE Mutations in BRAF, NRAS, KRAS and PTEN, that are known to be involved in thyroid cancer biology, were detected in seven FNA samples. 24834793 2015
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.480 GeneticVariation disease BEFREE To analyze FTH samples for known recurrent genetic and epigenetic driver events in thyroid neoplasms such as activating mutations in proto-oncogenes BRAF and NRAS and promoter hypermethylation of tumor suppressor genes CDKN2A, PTEN, and RASSF1A. 25229773 2014
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.480 GeneticVariation disease LHGDN Familial non-medullary thyroid carcinoma (FNMTC): analysis of fPTC/PRN, NMTC1, MNG1 and TCO susceptibility loci and identification of somatic BRAF and RAS mutations. 18310288 2008
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.480 AlteredExpression disease LHGDN High prevalence of RET, RAS, and ERK expression in Hashimoto's thyroiditis and in papillary thyroid carcinoma in the Korean population. 17900235 2007
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.480 GeneticVariation disease BEFREE The prevalence of H-RAS, K-RAS, and N-RAS gene mutations in thyroid tumors according to malignancy and histology is controversial. 12788883 2003
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.480 CausalMutation disease CGI