NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040137
Disease: Thyroid Nodule
Thyroid Nodule
0.040 GeneticVariation disease BEFREE Objectives To determine the diagnostic value of HRAS, KRAS, and NRAS mutations in fine-needle aspiration biopsies of thyroid nodules that are nondiagnostic on cytology. 28116986 2017
CUI: C0040137
Disease: Thyroid Nodule
Thyroid Nodule
0.040 GeneticVariation disease BEFREE Preoperative RAS mutation detection in thyroid nodules carries a substantial risk of cancer with a greater risk associated with HRAS and NRAS. 27863786 2017
CUI: C0040137
Disease: Thyroid Nodule
Thyroid Nodule
0.040 GeneticVariation disease BEFREE We evaluated the utility of NRAS codon 61 (NRAS61) mutation analysis and core needle biopsy (CNB) for the diagnosis of thyroid nodules previously diagnosed as AUS. 26547216 2016
CUI: C0040137
Disease: Thyroid Nodule
Thyroid Nodule
0.040 GeneticVariation disease BEFREE Thyroid nodules with KRAS mutations are different from nodules with NRAS and HRAS mutations with regard to cytopathologic and histopathologic outcome characteristics. 25132659 2014