NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Disease: Childhood T Lymphoblastic Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332998
Disease: Childhood T Lymphoblastic Lymphoma
Childhood T Lymphoblastic Lymphoma 		0.020 GeneticVariation disease BEFREE We present a unique case of a child with concurrent JMML and T-lymphoblastic lymphoma in which an identical missense mutation in NRAS was found in both the neoplastic JMML and T-LBL cells. 24610751 2014
CUI: C1332998
Disease: Childhood T Lymphoblastic Lymphoma
Childhood T Lymphoblastic Lymphoma 		0.020 GeneticVariation disease BEFREE Genetic analyses revealed that both cell populations bore +21, while a G13D mutation of the NRAS gene and monosomy 18 were detected only in the pro-T LBL. 25228298 2014