NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Disease: Spitzoid melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3495721
Disease: Spitzoid melanoma
Spitzoid melanoma 		0.040 GeneticVariation disease BEFREE Both Spitz naevi and spitzoid melanoma had a lower combined BRAF and NRAS mutation frequency compared with common acquired naevi (P = 0.0001) and common forms of melanoma (P = 0.0072), respectively. 19438459 2009
CUI: C3495721
Disease: Spitzoid melanoma
Spitzoid melanoma 		0.040 GeneticVariation disease BEFREE In contrast to the majority of cutaneous melanomas, activating hot-spot mutations in B-RAF or N-RAS were not involved in the pathogenesis of Spitzoid melanoma. 16421887 2006
CUI: C3495721
Disease: Spitzoid melanoma
Spitzoid melanoma 		0.040 GeneticVariation disease BEFREE Analysis of mutations in B-RAF, N-RAS, and H-RAS genes in the differential diagnosis of Spitz nevus and spitzoid melanoma. 16096402 2005
CUI: C3495721
Disease: Spitzoid melanoma
Spitzoid melanoma 		0.040 Biomarker disease BEFREE There are genetic similarities with respect to the B-RAF, N-RAS, and H-RAS genes between Spitzoid melanoma and Spitz nevi. 15503312 2004