OAS2, 2'-5'-oligoadenylate synthetase 2, 4939

N. diseases: 38; N. variants: 4
Disease: Virus Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.020 Biomarker group BEFREE Although all three enzymatically active OAS proteins in humans--OAS1, OAS2, and OAS3--synthesize 2-5A upon binding dsRNA, it is unclear which are responsible for RNase L activation during viral infection. 26858407 2016
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.020 GeneticVariation group BEFREE Our results suggest that OAS2 haplotypes are associated with differential susceptibility to clinical outcomes of dengue virus infection. 24819159 2015