|
Tooth Attrition
|
0.010 |
Biomarker
|
disease |
BEFREE |
These findings enrich a nascent body of literature on mechanisms associated with attrition from OAT due to incarceration and emphasize the need for programs to divert people with OUD from incarceration to increase engagement and retention in OAT.
|
31821129 |
2020 |
|
Sleep Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Those with history of comorbid psychiatric illnesses (except sleep disorders), on any other substance in high-risk category (based on WHO-Alcohol Smoking Substance Involvement Screening Test (ASSIST)), or on any other psychotropic medications (in addition to OAT with buprenorphine) were excluded.
|
30964756 |
2020 |
|
Anxiety
|
0.010 |
Biomarker
|
disease |
BEFREE |
<i>Conclusions:</i> Insomnia was common in people receiving OAT and using opioids non-medically, and associated with anxiety and depression.
|
31131668 |
2019 |
|
Anxiety Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
<i>Conclusions:</i> Insomnia was common in people receiving OAT and using opioids non-medically, and associated with anxiety and depression.
|
31131668 |
2019 |
|
Non-Small Cell Lung Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Inhibition of OAT may also represent a new therapeutic strategy of NSCLC.
|
30549035 |
2019 |
|
Mental Depression
|
0.010 |
Biomarker
|
disease |
BEFREE |
<i>Conclusions:</i> Insomnia was common in people receiving OAT and using opioids non-medically, and associated with anxiety and depression.
|
31131668 |
2019 |
|
Depressive disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
<i>Conclusions:</i> Insomnia was common in people receiving OAT and using opioids non-medically, and associated with anxiety and depression.
|
31131668 |
2019 |
|
Diabetes
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In addition, western blotting results showed that the expression of OAT and FBP protein increased significantly in the diabetes group, while elongation factor 2 decreased significantly and FABP do not have significant difference in the diabetes group.
|
30035378 |
2019 |
|
Diabetes Mellitus
|
0.010 |
AlteredExpression
|
group |
BEFREE |
In addition, western blotting results showed that the expression of OAT and FBP protein increased significantly in the diabetes group, while elongation factor 2 decreased significantly and FABP do not have significant difference in the diabetes group.
|
30035378 |
2019 |
|
Macular Edema, Cystoid
|
0.010 |
Biomarker
|
disease |
BEFREE |
Optical Coherence Tomography Angiography and Macular Vessel Density Analysis of Cystoid Macular Edema in Gyrate Atrophy.
|
31344241 |
2019 |
|
Degenerative polyarthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Valgus HTO combined with OAT is one treatment option for osteonecrosis of the medial femoral condyle with osteoarthritis.
|
30245092 |
2019 |
|
Adult Liver Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The inhibition of ornithine aminotransferase (OAT), a pyridoxal 5'-phosphate-dependent enzyme, has been implicated as a treatment for hepatocellular carcinoma (HCC), the most common form of liver cancer, for which there is no effective treatment.
|
31251613 |
2019 |
|
Liver and Intrahepatic Biliary Tract Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The inhibition of ornithine aminotransferase (OAT), a pyridoxal 5'-phosphate-dependent enzyme, has been implicated as a treatment for hepatocellular carcinoma (HCC), the most common form of liver cancer, for which there is no effective treatment.
|
31251613 |
2019 |
|
Depressed mood
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
<i>Conclusions:</i> Insomnia was common in people receiving OAT and using opioids non-medically, and associated with anxiety and depression.
|
31131668 |
2019 |
|
Sleeplessness
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
<i>Conclusions:</i> Insomnia was common in people receiving OAT and using opioids non-medically, and associated with anxiety and depression.
|
31131668 |
2019 |
|
Alzheimer's Disease
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We found that common and rare variants of L3MBTL2 were significantly associated with AD. mRNA expression levels of 18 MDD risk genes, in particular SORCS3 and OAT, were differentially expressed in AD brain tissues.
|
30010129 |
2018 |
|
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Noteworthy, TLR4-activation seems as the most promising way of cancer immunotherapy, as a high percentage of molecules which demonstrated clinical benefits in cancer treatment are activators of TLR4, including BCG vaccine, monophosphoryl lipid A and picibanil (OKT-432).
|
30025492 |
2018 |
|
Chronic Obstructive Airway Disease
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Two genes (OAT and GRIK2) displayed significantly increased gene expression in cells isolated from individuals with COPD.
|
29527240 |
2018 |
|
Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
The upregulation of ornithine aminotransferase was associated with pathological grade and clinical tumor node metastasis stage.
|
30198174 |
2018 |
|
Oligospermia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Methylome and transcriptome analysis on individual oligoasthenoteratozoospermia (OAT [MF]) blastocysts.
|
29961538 |
2018 |
|
Muscle damage
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Effects of oat protein supplementation on skeletal muscle damage, inflammation and performance recovery following downhill running in untrained collegiate men.
|
30094437 |
2018 |
|
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
Noteworthy, TLR4-activation seems as the most promising way of cancer immunotherapy, as a high percentage of molecules which demonstrated clinical benefits in cancer treatment are activators of TLR4, including BCG vaccine, monophosphoryl lipid A and picibanil (OKT-432).
|
30025492 |
2018 |
|
Neuralgia
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Focal adhesion and the T cell receptor signaling pathway may be significantly linked with NP, and GSK3B, OAT and ODC1 may be potential targets for the treatment of NP.
|
28260076 |
2017 |
|
Memory impairment
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Post-test intra-Acb shell of ACPA (0.002 μg/rat), CP94253 (0.5 and 5 ng/rat) and GR127935 (5 ng/rat) increased the percentage of open-arms time (%OAT) in the EPM task compared to the control group, indicating aversive memory deficit.
|
28287814 |
2017 |
|
Water Stress
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The expression of proline biosynthetic genes including pyrroline-5-carboxylase synthase1, 1-pyrroline-5-carboxylase synthase2, and 1-pyrroline-5-carboxylase reductase was induced, while the ornithine aminotransferase transcript showed a variable response and the expression of proline catabolic genes including proline dehydrogenase1, proline dehydrogenase1, and proline 5-carboxylate dehydrogenase was reduced by water stress.
|
28286732 |
2017 |