Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE Higher serum lectin-like oxidized low-density lipoprotein receptor-1 in patients with stable coronary artery disease is associated with major adverse cardiovascular events: A multicentre pilot study. 30799974 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE Association Between Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 and Coronary Artery Disease in Psoriasis. 31746956 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Several genetic variants of LOX-1 are associated with the risk and severity of coronary artery disease. 30381837 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE Soluble LOX-1 (sLOX-1), a fragment of the main LOX-1 molecule, is being investigated as a diagnostic marker because it has been shown to be present in increased quantities in patients with hypertension, diabetes, metabolic syndrome and coronary artery disease. 31336709 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Are IVS4 SNPs of OLR1 gene associated with coronary artery disease: Is there a linkage between IVS4 SNPs? 29558038 2018
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE Also, it indicated that sodium/hydrogen exchanger 3 (SLC9A3), Prostaglandin G/H synthase 2 (PTGS2), Oxidized low-density lipoprotein receptor 1 (OLR1), and fibrinogen gamma chain (FGG) may be potential therapeutic targets for CHD. 28629174 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Scavenger Receptor LOX1 Genotype Predicts Coronary Artery Disease in Patients With Familial Hypercholesterolemia. 28941610 2017
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Our results suggest that antagonism between SRSF1 and SRSF2/HMGA1, and differential recognition of their regulatory motifs depending on the identity of the rs3736234 polymorphism, influence OLR1 exon 5 inclusion and the efficiency of Ox-LDL uptake, with potential implications for atherosclerosis and coronary disease. 25904137 2015
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE Many authors have shown the possibility to use LOX-1 as a good marker for the diagnosis and prognosis of coronary artery disease because it is easy to measure and more sensitive than other markers commonly used in the routine of laboratory medicine. 23934117 2013
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE The LOX-1 3'UTR188CT polymorphism and coronary artery disease in Turkish patients. 21901421 2012
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Is LOX-1 K167N polymorphism protective for coronary artery disease? 20023241 2010
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Several studies have been carried out to explore the role of OLR-1 gene polymorphisms in the risk of coronary artery disease. 20136518 2010
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE On the association of the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction or coronary artery disease. 16251892 2006
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE The 3'-UTR C>T polymorphism of the oxidized LDL-receptor 1 (OLR1) gene does not associate with coronary artery disease in Italian CAD patients or with the severity of coronary disease. 16829343 2006
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1 (LOX1) gene and the risk of coronary artery disease. 12810610 2003
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 GeneticVariation disease BEFREE Manipulating LOX-1 activity might be a useful therapeutic and preventative approach for coronary artery disease, especially for individuals with the G501C genotype of OLR1. 12646194 2003