Disease: Myocardial Infarction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 Biomarker disease BEFREE The cardiac lectin-like oxidized low-density-lipoprotein receptor-1 is activated by oxidative stress in ischaemia-reperfusion injury, inducing apoptosis in cardiomyocytes through the deleterious NF-kB pathway, while the administration of anti-lectin-like oxidized low-density-lipoprotein receptor-1 antibody suppresses apoptosis and reduces the extent of myocardial infarction. 31782085 2020
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 GeneticVariation disease BEFREE In humans, LOX-1 gene polymorphisms were associated with increased susceptibility to myocardial infarction. 23935243 2013
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 Biomarker disease BEFREE The lectin-like oxidized LDL receptor LOX-1 (encoded by OLR1) is believed to play a key role in atherogenesis and some reports suggest an association of OLR1 polymorphisms with myocardial infarction (MI). 18384690 2008
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 Biomarker disease BEFREE LOX-1 is increasingly viewed as a vascular disease biomarker and a potential therapeutic target in heart attack and stroke prevention. 18092947 2008
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 GeneticVariation disease BEFREE Recently, a 3'-UTR (188 C>T) SNP in the OLR1 gene has been reported to be associated with coronary artery stenosis and myocardial infarction. 16829343 2006
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 GeneticVariation disease BEFREE Independent association genetic studies have implicated OLR1 gene variants in myocardial infarction (MI) susceptibility. 15976314 2005
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 GeneticVariation disease BEFREE Recently, LOX-1 gene polymorphism (G501C) was reported to be associated with myocardial infarction (MI). 15562935 2004
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 Biomarker disease CTD_human Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction. 14684693 2003
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 Biomarker disease CTD_human These findings suggest that OLR1 or a neighboring gene linked with G501C SNP is important for the incidence of MI. 12646194 2003
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 Biomarker disease LHGDN Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction. 14684693 2003
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 GeneticVariation disease BEFREE These findings suggest that OLR1 or a neighboring gene linked with G501C SNP is important for the incidence of MI. 12646194 2003
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.490 SusceptibilityMutation disease CLINVAR