OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Disease: Morphine Dependence ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026552
Disease: Morphine Dependence
Morphine Dependence 		0.330 Biomarker disease BEFREE We advocate that targeting MOR selectively in the DG NSC population might offer a novel therapeutic intervention for morphine addiction. 30728362 2019
CUI: C0026552
Disease: Morphine Dependence
Morphine Dependence 		0.330 Biomarker disease BEFREE These findings may help to reveal the mechanism that AQP4, GLT-1, and MOR form protein complex and participate in morphine dependence, and deeply understand the reason that AQP4 deficiency maintains extracellular glutamate homeostasis and attenuates morphine dependence, moreover emphasizes the function of astrocyte in morphine dependence. 28341892 2017
CUI: C0026552
Disease: Morphine Dependence
Morphine Dependence 		0.330 AlteredExpression disease BEFREE This study aims to explore the relationship among morphine addiction, reactive oxygen species (ROS) and expression of μ-opioid receptor (MOR) in differentiated SH-SY5Y cells. 25623851 2015
CUI: C0026552
Disease: Morphine Dependence
Morphine Dependence 		0.330 Biomarker disease CTD_human Effects of beta-funaltrexamine (beta-FNA) on morphine dependence in rats and monkeys. 3720824 1986