OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 GeneticVariation disease BEFREE There was no statistically significant difference in genotypic and allelic frequencies of OPRM1 A118G SNP between HCs and SZ/BD patients. 29497192 2019
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 Biomarker disease BEFREE Reduced mu opioid receptor availability in schizophrenia revealed with [<sup>11</sup>C]-carfentanil positron emission tomographic Imaging. 31582737 2019
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 GeneticVariation disease BEFREE We conducted a case-control study to investigate the genetic association between OPRM1 polymorphisms and SZ among the Han chinese population. 23560613 2013
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 Biomarker disease PSYGENET We conducted a case-control study to investigate the genetic association between OPRM1 polymorphisms and SZ among the Han chinese population. 23560613 2013
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 Biomarker disease PSYGENET Overall these data suggest that mu opioid receptor availability is decreased in the brains of people with schizophrenia who died as a result of suicide, which would be consistent with increased levels of endogenous ligands occupying these receptors. 22925223 2012
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 Biomarker disease BEFREE Overall these data suggest that mu opioid receptor availability is decreased in the brains of people with schizophrenia who died as a result of suicide, which would be consistent with increased levels of endogenous ligands occupying these receptors. 22925223 2012
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 GeneticVariation disease BEFREE The study was focused on the relationship between the functional A118G polymorphism of the OPRM1 gene (rs1799971) and schizophrenia in groups of 130 male patients and 452 male controls. 20112002 2010
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 Biomarker disease PSYGENET The study was focused on the relationship between the functional A118G polymorphism of the OPRM1 gene (rs1799971) and schizophrenia in groups of 130 male patients and 452 male controls. 20112002 2010
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.360 GeneticVariation disease LHGDN Mu opioid receptor gene polymorphism and neuroleptic-induced tardive dyskinesia in patients with schizophrenia. 14623376 2003