OPRM1, opioid receptor mu 1, 4988

N. diseases: 370; N. variants: 42
Disease: Hyperalgesia, Thermal ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.310 AlteredExpression phenotype BEFREE Inhibition of DNMT3a catalytic activity with DNMT inhibitor RG108 significantly blocked the increase in methylation of the MOR promoter, and then upregulated MOR expression and attenuated thermal hyperalgesia in neuropathic pain mice. 29075135 2017
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.310 Biomarker phenotype CTD_human Molecular interaction in the mouse PAG between NMDA and opioid receptors in morphine-induced acute thermal nociception. 17996026 2008