Carcinoma of lung
|
0.600 |
GeneticVariation
|
disease |
UNIPROT |
We also found loss of heterozygosity in the lung cancer, suggesting that TSSC5 may be a conventional tumor suppressor gene in the adult human lung and an imprinted tumor suppressor gene in the fetal kidney.
|
9751628 |
1998 |
Carcinoma of lung
|
0.600 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
Carcinoma of lung
|
0.600 |
CausalMutation
|
disease |
CGI |
|
|
|
Lung Neoplasms
|
0.500 |
CausalMutation
|
group |
CGI |
|
|
|
Lung Neoplasms
|
0.500 |
Biomarker
|
group |
CTD_human |
|
|
|
Malignant neoplasm of lung
|
0.500 |
Biomarker
|
disease |
CTD_human |
|
|
|
Malignant neoplasm of lung
|
0.500 |
CausalMutation
|
disease |
CGI |
|
|
|
Breast Carcinoma
|
0.460 |
Biomarker
|
disease |
BEFREE |
Our results suggest that SLC22A18 may act as a tumor suppressor by regulating the expression levels of cell growth-related proteins, and vinca alkaloids might show therapeutic efficacy against low-SLC22A18-expressing breast cancer.
|
30145211 |
2018 |
Breast Carcinoma
|
0.460 |
AlteredExpression
|
disease |
BEFREE |
The results of Kaplan-Meier analysis indicated that SLC22A18 expression was associated with relapse-free survival (RFS) of breast cancer.
|
21144813 |
2011 |
Breast Carcinoma
|
0.460 |
Biomarker
|
disease |
BEFREE |
Gain of imprinting of SLC22A18 sense and antisense transcripts in human breast cancer.
|
16624517 |
2006 |
Breast Carcinoma
|
0.460 |
AlteredExpression
|
disease |
BEFREE |
HET/SAF-B protein and mRNA were detected at varying levels in all of the eight breast cancer cell lines examined.
|
10999774 |
2000 |
Breast Carcinoma
|
0.460 |
GeneticVariation
|
disease |
BEFREE |
Because this region frequently is altered in neoplasms and in the genetic disease Beckwith-Wiedemann syndrome, we carried out a mutational analysis in tumor cell lines and Beckwith-Wiedemann syndrome samples that resulted in the identification of genetic alterations in the BWR1A gene: an insertion that introduced a stop codon in the breast cancer cell line BT549 and a point mutation in the rhabdomyosarcoma cell line TE125-T.
|
9520460 |
1998 |
Breast Carcinoma
|
0.460 |
Biomarker
|
disease |
BEFREE |
We were able to show that HET is localized in the nuclear matrix in various breast cancer cell lines.
|
9328833 |
1997 |
Breast Carcinoma
|
0.460 |
Biomarker
|
disease |
CTD_human |
|
|
|
Breast Carcinoma
|
0.460 |
Biomarker
|
disease |
HPO |
|
|
|
Embryonal Rhabdomyosarcoma
|
0.400 |
GeneticVariation
|
disease |
ORPHANET |
Transcriptional map of 170-kb region at chromosome 11p15.5: identification and mutational analysis of the BWR1A gene reveals the presence of mutations in tumor samples.
|
9520460 |
1998 |
Embryonal Rhabdomyosarcoma
|
0.400 |
Biomarker
|
disease |
HPO |
|
|
|
Malignant neoplasm of breast
|
0.360 |
Biomarker
|
disease |
BEFREE |
Our results suggest that SLC22A18 may act as a tumor suppressor by regulating the expression levels of cell growth-related proteins, and vinca alkaloids might show therapeutic efficacy against low-SLC22A18-expressing breast cancer.
|
30145211 |
2018 |
Malignant neoplasm of breast
|
0.360 |
AlteredExpression
|
disease |
BEFREE |
The results of Kaplan-Meier analysis indicated that SLC22A18 expression was associated with relapse-free survival (RFS) of breast cancer.
|
21144813 |
2011 |
Malignant neoplasm of breast
|
0.360 |
Biomarker
|
disease |
BEFREE |
Gain of imprinting of SLC22A18 sense and antisense transcripts in human breast cancer.
|
16624517 |
2006 |
Malignant neoplasm of breast
|
0.360 |
AlteredExpression
|
disease |
BEFREE |
HET/SAF-B protein and mRNA were detected at varying levels in all of the eight breast cancer cell lines examined.
|
10999774 |
2000 |
Malignant neoplasm of breast
|
0.360 |
GeneticVariation
|
disease |
BEFREE |
Because this region frequently is altered in neoplasms and in the genetic disease Beckwith-Wiedemann syndrome, we carried out a mutational analysis in tumor cell lines and Beckwith-Wiedemann syndrome samples that resulted in the identification of genetic alterations in the BWR1A gene: an insertion that introduced a stop codon in the breast cancer cell line BT549 and a point mutation in the rhabdomyosarcoma cell line TE125-T.
|
9520460 |
1998 |
Malignant neoplasm of breast
|
0.360 |
Biomarker
|
disease |
BEFREE |
We were able to show that HET is localized in the nuclear matrix in various breast cancer cell lines.
|
9328833 |
1997 |
Malignant neoplasm of breast
|
0.360 |
Biomarker
|
disease |
CTD_human |
|
|
|
Mammary Neoplasms
|
0.320 |
AlteredExpression
|
group |
BEFREE |
SPECIMENS AND METHODS: Immunohistochemistry was used to examine SLC22A18 protein expression in the breast tumors.
|
21144813 |
2011 |