PRDX1, peroxiredoxin 1, 5052

N. diseases: 237; N. variants: 3
Disease: Malignant neoplasm of esophagus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.340 AlteredExpression disease BEFREE We found that an antioxidant protein peroxiredoxin I (Prx I) was upregulated in human EC tissues as well as in EC cell lines. 27650197 2017
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.340 GeneticVariation disease BEFREE Our data suggested that polymorphisms of Prdx 1, 2 and 6 were not associated with esophageal cancer. 22215146 2012
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.340 Biomarker disease BEFREE Silencing Prx1 and/or Prx5 sensitizes human esophageal cancer cells to ionizing radiation and increases apoptosis via intracellular ROS accumulation. 21468086 2011
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.340 AlteredExpression disease BEFREE Except p21, Prdx1 (reported by us) and IGFBP3, the behaviour/expression of 12 highly responsive genes has still not been reported in esophageal cancer cells. 17671705 2007
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus 		0.340 Biomarker disease CTD_human Comparative proteomic analysis of esophageal squamous cell carcinoma. 15986332 2005