IL20, interleukin 20, 50604

N. diseases: 111; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Insulin-Dependent
0.310 Biomarker disease BEFREE Conversely, both IL-20 and transforming growth factor (TGF-β) decreased in T1D-EV<sup>+</sup> versus EV<sup>-</sup> , while IL-4, -6 and -13 did not show any changes. 28640379 2017
Diabetes Mellitus, Insulin-Dependent
0.310 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.310 Biomarker disease CTD_human We analyzed the expression of IL-20 and its receptor (R) in the kidneys of rats with HgCl(2)-induced acute renal failure. 18496552 2008
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute
0.310 AlteredExpression disease BEFREE We analyzed the expression of IL-20 and its receptor (R) in the kidneys of rats with HgCl(2)-induced acute renal failure. 18496552 2008
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.310 Biomarker disease BEFREE Our study established increased risk for MDD related to the IL20 and IL24 haplotype and suggests that cytokines may contribute to the pathogenesis of MDD. 19087313 2008
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.310 Biomarker disease PSYGENET Our study established increased risk for MDD related to the IL20 and IL24 haplotype and suggests that cytokines may contribute to the pathogenesis of MDD. 19087313 2008
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
CUI: C0342302
Disease: Brittle diabetes
Brittle diabetes
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
CUI: C3837958
Disease: Diabetes Mellitus, Ketosis-Prone
Diabetes Mellitus, Ketosis-Prone
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
CUI: C4554117
Disease: Diabetes Mellitus, Sudden-Onset
Diabetes Mellitus, Sudden-Onset
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker disease PSYGENET Polymorphisms in the interleukin-10 gene cluster are possibly involved in the increased risk for major depressive disorder. 19087313 2008
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency
0.300 Biomarker disease CTD_human Interleukin-20 induced cell death in renal epithelial cells and was associated with acute renal failure. 18496552 2008
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury
0.300 Biomarker disease CTD_human Interleukin-20 induced cell death in renal epithelial cells and was associated with acute renal failure. 18496552 2008
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker disease RGD Interleukin-20 targets renal cells and is associated with chronic kidney disease. 18639518 2008
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker disease RGD Interleukin-20 targets renal cells and is associated with chronic kidney disease. 18639518 2008
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.100 AlteredExpression disease BEFREE We analyzed levels of IL-20 receptor subunit A (IL-20RA), CD55, and receptor activator of nuclear factor kappaB (NF-κB) ligand (RANKL) in RA fibroblast-like synoviocytes (FLSs) using confocal microscopy. 31831038 2019
CUI: C0149745
Disease: Oral Ulcer
Oral Ulcer
0.100 GeneticVariation disease GWASCAT Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci. 30837455 2019
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.100 Biomarker disease BEFREE The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis. 30319661 2018
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.100 Biomarker disease BEFREE IL-20 is emerging as a potent angiogenic, chemotactic, and proinflammatory cytokine related to several chronic inflammatory bone disorders likes intervertebral disc herniation, rheumatoid arthritis (RA), osteoporosis, and bone fracture. 30250404 2018
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.100 Biomarker disease BEFREE IL-20 is emerging as a potent angiogenic, chemotactic, and proinflammatory cytokine related to several chronic inflammatory disorders likes psoriasis, atherosclerosis, cancer, liver fibrosis, and RA. 29690863 2018
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.100 Biomarker disease BEFREE IL-20 is emerging as a potent angiogenic, chemotactic, and proinflammatory cytokine related to several chronic inflammatory disorders likes psoriasis, atherosclerosis, and renal failure. 29999545 2018
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.100 Biomarker disease BEFREE IL-20 is emerging as a potent angiogenic, chemotactic, and proinflammatory cytokine related to several chronic inflammatory disorders likes psoriasis, atherosclerosis, cancer, liver fibrosis, and RA. 29690863 2018
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.100 Biomarker disease BEFREE This review focuses on current knowledge of IL-20's involvement in the pathogenesis of rheumatoid arthritis. 26297177 2017
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.100 AlteredExpression disease BEFREE The expression of IL-20 in RA synovial tissue was particularly associated with macrophages and neutrophil granulocytes, but also with synovial fibroblasts and lymphocytes. 28662439 2017
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.100 Biomarker disease BEFREE The IL-20 subfamily of cytokines has been reported to act at epithelial sites and contribute to psoriasis, wound healing, and anti-inflammatory effects during <i>S. aureus</i> infection. 28424238 2017