Autosomal Recessive Parkinsonism
|
0.400 |
Biomarker
|
disease |
BEFREE |
PARK2 is an autosomal recessive parkinsonism caused by parkin gene mutations.
|
26626785 |
2017 |
Autosomal Recessive Parkinsonism
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells.
|
26558463 |
2015 |
Autosomal Recessive Parkinsonism
|
0.400 |
Biomarker
|
disease |
CTD_human |
A recurrent mutation in PARK2 is associated with familial lung cancer.
|
25640678 |
2015 |
Autosomal Recessive Parkinsonism
|
0.400 |
Therapeutic
|
disease |
CTD_human |
A recurrent mutation in PARK2 is associated with familial lung cancer.
|
25640678 |
2015 |
Autosomal Recessive Parkinsonism
|
0.400 |
Biomarker
|
disease |
CTD_human |
Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells.
|
26558463 |
2015 |
Autosomal Recessive Parkinsonism
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism.
|
23046578 |
2013 |
Autosomal Recessive Parkinsonism
|
0.400 |
Biomarker
|
disease |
CTD_human |
Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism.
|
23046578 |
2013 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Parkin (PARK2) gene mutations are the predominant cause of autosomal recessive parkinsonism.
|
22445249 |
2012 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Parkin (PARK2) gene mutations are the major cause of autosomal recessive parkinsonism.
|
18987353 |
2009 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Mutations in PINK1 and PARK2 cause autosomal recessive parkinsonism, a neurodegenerative disorder that is characterized by the loss of dopaminergic neurons.
|
19684592 |
2009 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Mutations of the Park2 gene cause autosomal recessive parkinsonism with neuropathological findings consistent with neurofibrillary tangles and tau immunoreactive lesions.
|
18022644 |
2008 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Herein, we demonstrate the utility of this technique by rapidly identifying a disease causing microdeletion within the PARK2 gene in a family with autosomal recessive Parkinsonism.
|
17676595 |
2007 |
Autosomal Recessive Parkinsonism
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease.
|
16914382 |
2006 |
Autosomal Recessive Parkinsonism
|
0.400 |
Biomarker
|
disease |
CTD_human |
Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease.
|
16914382 |
2006 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Early-onset autosomal recessive parkinsonism is associated with parkin gene mutations.
|
15197707 |
2004 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Mutations in the parkin gene are responsible for autosomal recessive parkinsonism.
|
14678753 |
2003 |
Autosomal Recessive Parkinsonism
|
0.400 |
Biomarker
|
disease |
CTD_human |
Parkin disease: a phenotypic study of a large case series.
|
12764051 |
2003 |
Autosomal Recessive Parkinsonism
|
0.400 |
Therapeutic
|
disease |
CTD_human |
Parkin disease: a phenotypic study of a large case series.
|
12764051 |
2003 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Autosomal recessive parkinsonism linked to parkin gene in a Tunisian family. Clinical, genetic and pathological study.
|
12781588 |
2003 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Parkin gene mutations have been detected in families with early-onset autosomal recessive parkinsonism.
|
12815654 |
2003 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
One early onset subject presented a mutation in the parkin gene consistent with autosomal recessive parkinsonism.
|
12548339 |
2002 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Autosomal recessive parkinsonism associated with mutations in the parkin gene represents a monogenic form of hereditary parkinsonism.
|
11911988 |
2002 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Parkin gene mutations are present in Spanish patients with early onset and/or an autosomal recessive parkinsonism.
|
12397156 |
2002 |
Autosomal Recessive Parkinsonism
|
0.400 |
Biomarker
|
disease |
CTD_human |
Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36.
|
11254447 |
2001 |
Autosomal Recessive Parkinsonism
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
On the other hand, mutations in the parkin gene cause autosomal recessive parkinsonism of early onset.
|
11697518 |
2001 |