SERPINA5, serpin family A member 5, 5104

N. diseases: 185; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008370
Disease: Cholestasis
Cholestasis
0.300 Biomarker disease CTD_human "Integrative ""-Omics"" Analysis in Primary Human Hepatocytes Unravels Persistent Mechanisms of Cyclosporine A-Induced Cholestasis." 27989131 2016
CUI: C0236733
Disease: Amphetamine-Related Disorders
Amphetamine-Related Disorders
0.300 Biomarker group CTD_human Genome-wide association for methamphetamine dependence: convergent results from 2 samples. 18316681 2008
CUI: C0236804
Disease: Amphetamine Addiction
Amphetamine Addiction
0.300 Biomarker disease CTD_human Genome-wide association for methamphetamine dependence: convergent results from 2 samples. 18316681 2008
CUI: C0236807
Disease: Amphetamine Abuse
Amphetamine Abuse
0.300 Biomarker disease CTD_human Genome-wide association for methamphetamine dependence: convergent results from 2 samples. 18316681 2008
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.100 Biomarker disease BEFREE Remote ischaemic conditioning for myocardial infarction or elective PCI: systematic review and meta-analyses of randomised trials. 29911392 2020
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 Biomarker disease BEFREE Moreover, higher incidence of repeat revascularization after PCI in diabetic AMI patients a major concern until recently. 31420948 2020
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome
0.100 Biomarker disease BEFREE AT1R (rs 5182) CT genotype is mildly associated with STEMI (OR = 1.1), but also prone to have PCI after ACS attack (OR = 1.6) while TT genotype has a risk to get less improvement (OR = 1.8). 31195108 2020
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome
0.100 Biomarker disease BEFREE We describe the incidence, timing, and characteristics of stent thrombosis and its consequences in patients with atrial fibrillation (AF) in the AUGUSTUS trial<sup>1</sup> who received a coronary stent during their qualifying admission (acute coronary syndrome [ACS] or elective percutaneous coronary intervention [PCI]) and the randomized treatment effects of low-dose aspirin (compared with placebo) and apixaban (compared with vitamin K antagonist [VKA]) on the risk of stent thrombosis. 31707833 2020
ST segment elevation myocardial infarction
0.100 Biomarker disease BEFREE The indication for PCI was chronic stable angina in 46.1% (n=26), non-ST elevation acute coronary syndrome (NSTEACS) in 33.3% (n=18) and ST-elevation myocardial infarction (STEMI) in 18.5% (n=10) of patients. 31130523 2020
ST segment elevation myocardial infarction
0.100 Biomarker disease BEFREE In the transition from fibrinolysis to primary PCI, the HERO trials help refine STEMI ECG interpretation and Q wave analysis potentially alters future management. 30117751 2020
ST segment elevation myocardial infarction
0.100 GeneticVariation disease BEFREE From 434,172 low-risk, uncomplicated ACS patients eligible for early discharge (STEMI 35%, UA/NSTEMI 65%) from the Premier database, we identified ACS care pathways, by stratifying low-risk, uncomplicated STEMI and UA/NSTEMI patients by access site for PCI (trans-radial intervention [TRI] vs transfemoral intervention [TFI]) and by length of stay (LOS). 31812224 2020
ST segment elevation myocardial infarction
0.100 GeneticVariation disease BEFREE AT1R (rs 5182) CT genotype is mildly associated with STEMI (OR = 1.1), but also prone to have PCI after ACS attack (OR = 1.6) while TT genotype has a risk to get less improvement (OR = 1.8). 31195108 2020
CUI: C3275069
Disease: Chronic Total Occlusion Vessel
Chronic Total Occlusion Vessel
0.100 Biomarker disease BEFREE The application of the retrograde approach has dramatically improved success rates of CTO PCI. 30912215 2020
CUI: C0005890
Disease: Body Height
Body Height
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 Biomarker disease BEFREE As confirmed by our results, FFR and CFR are complementary; they could jointly contribute to better PCI guidance through the CFR-to-FFR ratio in patients with coronary artery disease. 30616240 2019
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 Biomarker disease BEFREE Twelve (86%) patients underwent PCI for stable coronary artery disease and 2 (14%) had unstable angina. 31175527 2019
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 Biomarker disease BEFREE We sought to examine the impact of AKI and its predictors in diabetic patients with multivessel coronary artery disease undergoing PCI vs. CABG. 31230933 2019
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.100 Biomarker disease BEFREE They dwell on the 'either/or' decision for selected patients suitable for both treatments, but provide little guidance for the majority of 'real world' patients with comorbidities precluding CABG, or complex coronary heart disease precluding PCI. 30846525 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE We sought to examine the impact of AKI and its predictors in diabetic patients with multivessel coronary artery disease undergoing PCI vs. CABG. 31230933 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE They dwell on the 'either/or' decision for selected patients suitable for both treatments, but provide little guidance for the majority of 'real world' patients with comorbidities precluding CABG, or complex coronary heart disease precluding PCI. 30846525 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE This study aimed to evaluate the value of Ang-2 in predicting cardiovascular events after elective PCI.This prospective study enrolled 97 patients with CHD who underwent elective PCI from 2013 to 2014. 30702576 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE As confirmed by our results, FFR and CFR are complementary; they could jointly contribute to better PCI guidance through the CFR-to-FFR ratio in patients with coronary artery disease. 30616240 2019
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.100 Biomarker disease BEFREE Twelve (86%) patients underwent PCI for stable coronary artery disease and 2 (14%) had unstable angina. 31175527 2019
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.100 Biomarker disease BEFREE So we evaluated the efficacy of the prasugrel/ticagrelor in patients with myocardial infarction (MI) and diabetes, a more high-risk patients group.From the Korea Acute Myocardial Infarction Registry-National Institute of Health, 3985 patients with MI and diabetes who underwent PCI were enrolled between November 2011 and December 2015. 30882670 2019
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.100 Biomarker disease BEFREE At 36 months MV PCI was associated with similar incidence of the composite endpoint (all-cause death, non-fatal myocardial infarction [MI], ACS-driven, revascularisation, or stroke) in both Cox proportional hazards model (hazard ratio [HR] 1.26; 95% confidence interval [CI] 0.75-2.11; p = 0.39) and propensity matched analysis (HR 1.28; 95% CI 0.75-2.21; p = 0.36). 30251246 2019