|
Acanthosis Nigricans
|
0.010 |
Biomarker
|
disease |
BEFREE |
With regard to keratin 6 mRNA, and the protein expression of keratin 6/16, KI-67, and proliferating cell nuclear antigen, the AN lesion showed moderate hyperproliferation.
|
7689823 |
1993 |
|
Acoustic Neuroma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Retinoblastoma-cyclin-dependent kinase pathway deregulation in vestibular schwannomas.
|
12352662 |
2002 |
|
Acoustic Neuroma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Does the proliferating cell nuclear antigen labeling index predict clinical behavior of vestibular schwannomas?
|
29309662 |
2018 |
|
Acquired cystic kidney disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
In this study, which used immunohistochemical methods with an antibody to proliferating cell nuclear antigen (PCNA), the proliferation index (PI) (percentage of PCNA positive cell nuclei among epithelial cells lining the renal cysts) was determined in 10 cases of autosomal dominant polycystic kidney disease (ADPKD), 8 cases of autosomal recessive polycystic kidney disease (ARPKD), and 8 cases of acquired cystic kidney disease (ACKD).
|
7703384 |
1995 |
|
Actinic keratosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In actinic keratosis, only half of the specimens showed overexpression of p53 associated with moderate or intense expression of PCNA.
|
10429981 |
1999 |
|
Acute Erythroblastic Leukemia
|
0.010 |
PosttranslationalModification
|
disease |
BEFREE |
The influence of the total flavonoids of Hedysarum polybotry on the proliferation, cell cycle, and expressions of p21Ras and proliferating cell nuclear antigen gene in erythroleukemia cell line K562.
|
22241506 |
2012 |
|
Acute hepatitis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In acute liver injury (AH and EX), there was a significant correlation between HGF mRNA expression and the PCNA labeling index (LI) in the liver (r = .87, P < .005).
|
8690400 |
1996 |
|
Acute leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
We have examined by two-dimensional polyacrylamide gel electrophoresis the expression of PCNA in various subtypes of childhood acute leukemia and have found differences in its expression according to subtype.
|
1975505 |
1990 |
|
Acute lymphocytic leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
IL17C transcripts showed the strongest negative correlation to PCNA in both ATL cohorts, which was replicated in two large cohorts of T- and B-cell acute lymphoid leukemia (ALL).
|
30303535 |
2019 |
|
Adenoameloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
There was no statistical difference in PCNA intensity of staining between ameloblastomas and AOTs (P > 0.05), whereas the p53 intensity in ameloblastomas was stronger than AOTs (P < 0.05).
|
21712626 |
2011 |
|
Adenocarcinoma
|
0.400 |
AlteredExpression
|
group |
BEFREE |
We show that mono-allelic loss of pten in the probasin-driven-ErbB-2 model resulted in increased nuclear cyclin D1 and proliferating cell nuclear antigen levels and decreased disease latency compared to either individual genetic model and, unlike the probasin-driven-ErbB-2 mice, progression to adenocarcinoma.
|
19443706 |
2009 |
|
Adenocarcinoma
|
0.400 |
Biomarker
|
group |
BEFREE |
Thirty-five adenomas and 60 adenocarcinomas were studied immunohistochemically concerning proliferating cell nuclear antigen positivity in tumor cell nuclei.
|
7956574 |
1994 |
|
Adenocarcinoma
|
0.400 |
Biomarker
|
group |
BEFREE |
These results demonstrated a progressive immunoreactivity for PCNA in the HP to AC sequence, while p53 positivity and aneuploidy seemed specific for colon carcinoma.
|
9673389 |
1998 |
|
Adenocarcinoma
|
0.400 |
Biomarker
|
group |
BEFREE |
A linear correlation between numbers of ISH signals and PCNA expression was not demonstrated, but there was a tendency of increasing PCNA positivity according to increasing numbers of ISH signals in adenocarcinomas of the lung and the tumor tissues which were over 50% positive PCNA expression.
|
7911024 |
1993 |
|
Adenocarcinoma
|
0.400 |
Biomarker
|
group |
BEFREE |
Results suggest that the PCNA index in cervical and endometrial adenocarcinomas and the pretreatment tumor volume in endometrial adenocarcinoma appeared to be potentially useful in predicting the immediate response to the chemotherapy.
|
9159335 |
1997 |
|
Adenocarcinoma
|
0.400 |
Biomarker
|
group |
CTD_human |
Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats.
|
19028472 |
2009 |
|
Adenocarcinoma
|
0.400 |
Biomarker
|
group |
LHGDN |
Helicobacter pylori-induced changes in the gastric mucosa are associated with mitogen-activated protein kinase (MAPK) activation.
|
17525639 |
2007 |
|
Adenocarcinoma
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Mean PCNA expression was higher in squamous carcinomas than in adenocarcinomas but there was marked intra-tumour variation in PCNA index in almost all cases.
|
1351473 |
1992 |
|
Adenocarcinoma
|
0.400 |
AlteredExpression
|
group |
BEFREE |
In order to explore the application value of DCE-MRI in clinical diagnosis and treatment, guide early clinical diagnosis, evaluate prognosis, guide clinical selection of treatment options and improve medical level, the expression of adenocarcinoma, its relationship with clinicopathology, and the significance of co-expression of the proliferating cell nuclear antigen (PCNA), Ki67 protein and cyclooxygenase 2 (COX-2) in breast cancer are analyzed.
|
31289003 |
2019 |
|
Adenocarcinoma
|
0.400 |
Biomarker
|
group |
BEFREE |
Biopsies of all 10 metastatic tumours (3 melanoma, 4 carcinoma and 3 adenocarcinoma) as well as 4 glioblastoma multiforme were positive for PCNA immunoexpression and supported the replication of HSV1716.
|
12898637 |
2003 |
|
Adenocarcinoma
|
0.400 |
Biomarker
|
group |
BEFREE |
Studies by PCNA (proliferating cell nuclear antigen) immunohistochemistry, showed that in over half of the gastric-type adenocarcinomas cases PCNA-positive cells tended to be localized within tumor tissues.
|
7903667 |
1993 |
|
Adenocarcinoma
|
0.400 |
Biomarker
|
group |
BEFREE |
The staining differences between LMP tumors and adenocarcinomas with antibodies against Ki-67, PCNA, and P-glycoprotein were not statistically significant.
|
9398993 |
1997 |
|
Adenocarcinoma
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The authors examined three cell-biological parameters--DNA status, proliferating cell-nuclear antigen (PCNA) immunostaining, and argyrophilic nucleolar-organizer region (AgNOR) counts--in surgically resected, formalin-fixed, paraffin-embedded urachal adenocarcinomas from 41 patients.
|
8600037 |
1996 |
|
Adenocarcinoma
|
0.400 |
Biomarker
|
group |
BEFREE |
A surprising finding was that S-phase percentage in adenocarcinomas was not parallel with PCNA-positive tumor cell numbers.
|
7729290 |
1995 |
|
Adenocarcinoma
|
0.400 |
AlteredExpression
|
group |
BEFREE |
The expression of proliferating cell nuclear antigen and p53 protein was analysed by immunocytochemical methods (PC10, CM1 antisera) in 139 patients with T1-2M0 prostatic adenocarcinomas followed-up for > 12 years. p53 protein was expressed in 21 (15%) tumours (15%), the fraction of positive nuclei being very low (mean SE, 1% +/- 0.7%).
|
7913085 |
1994 |