PCNA, proliferating cell nuclear antigen, 5111

N. diseases: 581; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.350 AlteredExpression group BEFREE We examined lung tumors 1-7 mm in largest dimension initiated in male Swiss mice by N-nitrosodimethylamine for pathologic type, Ki-ras mutations and levels of total Ki-ras p21, Ki-ras p21 bound to GTP, raf-1, Erk1 and Erk2 and their phosphorylated (activated) forms, and proliferating cell nuclear antigen. 10942532 2000
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.350 AlteredExpression group BEFREE To better understand the relationship between specific chromosome changes found in human lung tumors and their phenotypic consequences a the tissue level, an in situ hybridization (ISH) procedure of chromosome 17 and immunohistochemistry of proliferating cell nuclear antigen (PCNA) were done. 7911024 1993
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.350 AlteredExpression group BEFREE We evaluated the proliferative activity in 62 primary lung tumors by determining the cell's percentage of Ki-67 and immunoreactive PCNA (using MIB-1 and PCNA monoclonal antibodies), classifying Ki-67 and PCNA immunoreactivity into three score groups. 29940632 2018
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.350 Biomarker group BEFREE We show this association of PRPRT methylation with upregulation of the STAT3 target genes <i>Cyclin D1</i> and <i>Bcl-X<sub>L</sub></i> in patient derived lung tumour samples. 31595832 2019
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.350 Biomarker group CTD_human Levels of K-ras p21, raf-1, mitogen-activated protein kinases Erk 1 and 2, the phosphorylated-activated forms of Erk 1 and 2 (Erk 1P and 2P), and proliferating cell nuclear antigen (PCNA) were measured by immunoblotting in mouse lung tumors (5 to 9 mm in size) caused by N-nitrosodimethylamine (NDMA) and in control lungs. 11884234 2002
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.350 AlteredExpression group LHGDN [18F]FDG uptake and PCNA, Glut-1, and Hexokinase-II expressions in cancers and inflammatory lesions of the lung. 15967114 2005