Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
In addition, the interaction between circ-SMAD7 and proliferating cell nuclear antigen (PCNA) in glioma was studied by performing qRT-PCR and Western blot assay.
|
31799673 |
2019 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
S-phase Specific Downregulation of Human O<sup>6</sup>-Methylguanine DNA Methyltransferase (MGMT) and its Serendipitous Interactions with PCNA and p21<sup>cip1</sup> Proteins in Glioma Cells.
|
29510343 |
2018 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
In the rat glioma C6 orthotopic model, animal survival, flow cytometry for T cells within tumors, and immunohistochemistry for proliferating cell nuclear antigen (PCNA) and IDO were examined.
|
29993291 |
2018 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
DDC showed the highest sensitivity and specificity for glioma grading and was negatively correlated with Ki-67 and proliferating cell nuclear antigen expression.
|
30210702 |
2018 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The serine/threonine-protein kinase PFTAIRE 1 (PFTK1) is a member of the cyclin‑dependent kinase family that is highly expressed in several malignant tumors, including hepatocellular carcinoma, esophageal, breast and gastric cancers, and glioma.
|
28498444 |
2017 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
An integrated genomic and functional analysis to elucidate DNA damage signaling factors promoting self-renewal of glioma stem cells (GSCs) identified proliferating cell nuclear antigen (PCNA)-associated factor (<i>PAF</i>) up-regulation in glioblastoma.
|
29073105 |
2017 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Cell morphology, the level of DNA synthesis, the migration of cells, protein expression levels of proliferating cell nuclear antigen (PCNA) and the level of DNA oxidation in glioma tumours were investigated.
|
28562655 |
2017 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, a negative correlation was detected between the protein expression of PER2 and PCNA and EGFR in glioma.
|
25688509 |
2015 |
Glioma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In vitro, after the release of glioma cell lines from serum starvation, the expression of B23 was upregulated, as well as PCNA (Proliferating Cell Nuclear Antigen) and cyclin A.
|
26343305 |
2015 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
More importantly, TMEM45A siRNA treatment significantly down-regulated the proteins promoting cell cycles transition (Cyclin D1, CDK4 and PCNA) and cell invasion (MMP-2 and MMP-9), which indicted a possible mechanism underlying its functions on glioma.
|
26722455 |
2015 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Overexpression of rHSG displayed a strong effect on suppressing C6 cells proliferation in vitro and growth of glioma in vivo, which suggests the use of rHSG as a possible treatment strategy for glioma. p21Cip1, p27Kip1 and proliferating cell nuclear antigen were found to be involved in the tumor suppression mechanism of rHSG.
|
25362936 |
2014 |
Glioma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The XRCC1 Arg194Trp variant affects the proliferating cell nuclear antigen( PCNA) binding region, which suggests that this mutation may contribute to gliomagenesis and a number of articles have examine the association between XRCC1 Arg194Trp and the susceptibility to glioma.However, the results were conflicting.
|
25227852 |
2014 |
Glioma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We then demonstrate that the Dnmt1 phosphorylations by Akt and/or PKC abrogate the interactions of Dnmt1 with PCNA and UHRF1 in cellular and acellular studies including mass spectrometric analyses and the use of primary cultured patient-derived glioma.
|
20613874 |
2010 |