PCNA, proliferating cell nuclear antigen, 5111

N. diseases: 581; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0376154
Disease: Skin callus
Skin callus
0.020 AlteredExpression disease BEFREE TLR4 knockout promoted fracture healing, reduced the number of osteoclasts, increased bone callus volume (BV) and callus mineralized volume fraction (BV/TV%) (P <  0.05), increased the maximum torque and torsional stiffness of callus (P <  0.05), reduced TNF-α, IL-1β and IL-6 expression (P <  0.01), and increased the expression levels of β-catenin, Wnt4, Wnt5B, PCNA and BMP-2 (P <  0.01). 31796334 2020
CUI: C0376154
Disease: Skin callus
Skin callus
0.020 Biomarker disease BEFREE The number of proliferating cell nuclear antigen (PCNA)-positive subperiosteal osteoprogenitor cells was significantly increased in the calluses of the PTH-treated group on day 2, and TRAP+ multinucleated cells were significantly increased in areas of callus cancellous bone on day 7. 12412812 2002