PLCE1, phospholipase C epsilon 1, 51196

N. diseases: 114; N. variants: 57
Disease: Adenocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.320 AlteredExpression group BEFREE Previous reports show that phospholipase C epsilon-1 (<i>PLCE1</i>) expression is positively correlated with esophageal squamous cell carcinoma and gastric cardia adenocarcinomas; however, the expression of <i>PLCE1</i> in hepatocellular carcinoma (HCC) and its correlation with clinical outcome still remain unclear. 28031722 2017
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.320 GeneticVariation group BEFREE Similarly, rs2274223 in PLCE1 was associated with a reduced risk of oesophageal squamous cell cancer (OR 0.5; 95% CI 0.3-1.0), but not oesphageal adenocarcinoma. 22805490 2012
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.320 Biomarker group CTD_human A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. 20729852 2010