PLCE1, phospholipase C epsilon 1, 51196

N. diseases: 114; N. variants: 57
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019100
Disease: Severe Dengue
Severe Dengue
0.430 GeneticVariation disease BEFREE A previous genome-wide association study identified 2 susceptibility loci for severe dengue at MICB rs3132468 and PLCE1 rs3740360 and further work showed these mutations to be also associated with less severe clinical presentations. 28599625 2017
CUI: C0019100
Disease: Severe Dengue
Severe Dengue
0.430 GeneticVariation disease BEFREE SNPs in the MICB, TNF, CD209, FcγRIIA, TPSAB1, CLEC5A, IL10 and PLCE1 genes are associated with the risk or protection of severe dengue, and the findings have been replicated in different populations. 29133029 2017
CUI: C0019100
Disease: Severe Dengue
Severe Dengue
0.430 GeneticVariation disease BEFREE Genetic variants of MICB and PLCE1 and associations with non-severe dengue. 23536857 2013
CUI: C0019100
Disease: Severe Dengue
Severe Dengue
0.430 Biomarker disease CTD_human Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. 22001756 2011
CUI: C0019100
Disease: Severe Dengue
Severe Dengue
0.430 GeneticVariation disease GWASCAT Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. 22001756 2011