TLR7, toll like receptor 7, 51284

N. diseases: 276; N. variants: 13
Disease: Japanese Encephalitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014057
Disease: Japanese Encephalitis
Japanese Encephalitis 		0.050 Biomarker disease BEFREE CCL2 and CCL5 along with TLR7 may be associated with degree of pathogenesis of JE and could be putative therapeutic targets for preventing severe inflammation during viral encephalitis. 30585774 2019
CUI: C0014057
Disease: Japanese Encephalitis
Japanese Encephalitis 		0.050 AlteredExpression disease BEFREE The expression of TLR7 was increased significantly as compare to other TLR molecules post-JEV infection. 28265274 2017
CUI: C0014057
Disease: Japanese Encephalitis
Japanese Encephalitis 		0.050 Biomarker disease BEFREE The current findings suggest that pericytes might have pathological relevance in Japanese encephalitis-associated neuroinflammation through a TLR7-related mechanism. 28690034 2017
CUI: C0014057
Disease: Japanese Encephalitis
Japanese Encephalitis 		0.050 Biomarker disease BEFREE TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection. 24909816 2014
CUI: C0014057
Disease: Japanese Encephalitis
Japanese Encephalitis 		0.050 Biomarker disease BEFREE The microarray data also showed that TH1-5 modulated Socs-6, interleukin (IL)-6, Toll-like receptor (TLR)-1, TLR-7, caspase-4, interferon (IFN)-β1, ATF-3, and several immune-responsive genes to protect mice against JEV infection. 21726898 2011