TLR7, toll like receptor 7, 51284

N. diseases: 276; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.070 Biomarker disease BEFREE Publisher Correction: The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer. 31729370 2019
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.070 Biomarker disease BEFREE Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model. 31409607 2019
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.070 Biomarker disease BEFREE The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer. 31615993 2019
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.070 Biomarker disease BEFREE TLR7 has previously been demonstrated to be associated with the development of pancreatic cancer, and the release of cytokines and chemokines from other types of cancer cell; however, the specific expression induced by TLR7 agonists in pancreatic cancer cells remains to be elucidated. 26718740 2016
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.070 AlteredExpression disease BEFREE Our data demonstrate a stage-dependent upregulation of both TLR7 and TLR8 expression in pancreatic cancer. 26134824 2015
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.070 AlteredExpression disease BEFREE These results suggested that the activation of TLR7 suppresses the progression of pancreatic cancer. 26238718 2015
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.070 Biomarker disease BEFREE Since pancreatic tumorigenesis requires stromal expansion, we proposed that TLR7 ligation modulates pancreatic cancer by driving stromal inflammation. 23023703 2012