TLR7, toll like receptor 7, 51284

N. diseases: 276; N. variants: 13
Disease: Influenza A ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice. 30787331 2019
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE Early airway IFN-γ levels as well as the induction of lung NK cell CD69 expression and IFN-γ production in response to IAV infection were significantly attenuated in TLR7-deficient hosts. 29497422 2018
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE Toll-like receptor 7 (TLR-7) and melanoma differentiation-associated protein 5 (MDA5) receptors showed decreased expression in influenza A infected MK1-OSU cells, while only TLR-7 expression decreased in SD-PJEC cells. 29880757 2018
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE In contrast, stimulation with TLR7/8 ligand protected MDCs but not MDDCs from IAV infection. 25801434 2015
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE A comparative study of human TLR 7/8 stimulatory trimer compositions in influenza A viral genomes. 22363482 2012
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE Geriatric PBMCs produced significantly less IFN-alpha in response to live or inactivated influenza (a TLR7 ligand) but responded normally to CpG ODN (TLR9 ligand) and Guardiquimod (TLR7 ligand). 20182777 2010