WNT16, Wnt family member 16, 51384

N. diseases: 29; N. variants: 7
Disease: Degenerative polyarthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.050 GeneticVariation disease BEFREE However, WNT16 rs2908004 polymorphism was correlated with a decreased risk of OA, especially among females, smokers, non-drinkers and individuals with age < 60 years or BMI ≥ 25. 31560818 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.050 Biomarker disease BEFREE Wnt16 attenuates osteoarthritis progression through a PCP/JNK-mTORC1-PTHrP cascade. 30745310 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.050 Biomarker disease BEFREE Increased osteoarthritis in WNT16-deficient mice was associated with excessive activation of canonical WNT signalling. 27147711 2017
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.050 GeneticVariation disease BEFREE Hence, we hypothesized that allelic variations of WNT16 could influence the OA phenotype. 28766055 2017
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.050 AlteredExpression disease BEFREE Twenty four single nucleotide polymorphisms (SNPs) of genes showing differential expression between fractures and osteoarthritis (WNT4, WNT10A, WNT16 and SFRP1) were analyzed in DNA isolated from blood of 853 patients. 24096177 2013