VTA1, vesicle trafficking 1, 51534

N. diseases: 51; N. variants: 4
Disease: Colon Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.040 Biomarker disease BEFREE The tumor metastasis suppressor gene Drg-1 has been shown to suppress metastasis without affecting tumorigenicity in immunodeficient mouse models of prostate and colon cancer. 17178897 2006
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.040 Biomarker disease BEFREE On the other hand, we and others have demonstrated that the Drg-1 gene suppresses prostate and colon cancer metastases in mouse models. 15184886 2004
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.040 AlteredExpression disease BEFREE The Drg-1 gene has been shown to suppress tumor metastasis in animal models of prostate and colon cancer, and the expression of this gene is significantly reduced with advancement of prostate and breast cancers in clinical setting. 15520163 2004
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma 		0.040 Biomarker disease BEFREE We propose that Drg-1 suppresses colon cancer metastasis by inducing colon cancer cell differentiation and partially reversing the metastatic phenotype. 10676663 2000