SIRT7, sirtuin 7, 51547

N. diseases: 80; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma
0.020 Biomarker disease BEFREE In summary, our results show that SIRT7 promotes proliferation, migration, and invasion of osteosarcoma cells through targeting CDC4, suggesting a potential therapeutic target for SIRT7 based therapy for osteosarcoma. 28979804 2017
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma
0.020 Biomarker disease BEFREE Knockdown of SIRT7 sensitized osteosarcoma (U2OS) cells to DNA damage induced cell death by doxorubicin. 25445786 2015