Schizophrenia
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
We evaluated the PCQAP gene, which maps within the DGS/VCFS interval, as a potential candidate for schizophrenia susceptibility.
|
12497610 |
2003 |
Schizophrenia
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
These findings limit the role of exon 7 PCQAP polymorphisms in the pathogenesis of schizophrenia.
|
15318033 |
2004 |
Schizophrenia
|
0.320 |
GeneticVariation
|
disease |
LHGDN |
These findings limit the role of exon 7 PCQAP polymorphisms in the pathogenesis of schizophrenia.
|
15318033 |
2004 |
mathematical ability
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
|
30038396 |
2018 |
Renal Cell Carcinoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Here, we reported a case of Xp11 translocation RCC with a rare <i>MED15-TFE3</i> gene fusion by RNA sequencing.
|
31828108 |
2019 |
Neoplasm Metastasis
|
0.030 |
GeneticVariation
|
phenotype |
BEFREE |
Three of four tumors that metastasized, five of six that were poorly differentiated and all that were assigned a Gleason score higher than 8 (7/7) were methylated in the promoter of TIG1.
|
14691453 |
2004 |
Conventional (Clear Cell) Renal Cell Carcinoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Here, we reported a case of Xp11 translocation RCC with a rare <i>MED15-TFE3</i> gene fusion by RNA sequencing.
|
31828108 |
2019 |
Familial lichen amyloidosis
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
CGI hypermethylation at GSTP1, TIG1, PTGS2, and Reprimo was more frequent in PCA (42.3%, 9.5%, 2.4%, and 1.2%, respectively) compared to BPH (7.7%, 0%, 0%, and 0%, respectively) and healthy individuals (all 0%) with a statistical significant difference of GSTP1 (P < 0.0001) and TIG1 (P = 0.038).
|
18004747 |
2008 |
Stomach Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Expression and mutation analysis of TIG1 (tazarotene-induced gene 1) in human gastric cancer.
|
19806788 |
2009 |
Mesenchymal Cell Neoplasm
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We also report the first case of the corresponding mesenchymal neoplasm with MED15-TFE3 gene fusion.
|
29713041 |
2018 |
Refractory Cytopenia of Childhood
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Here, we reported a case of Xp11 translocation RCC with a rare <i>MED15-TFE3</i> gene fusion by RNA sequencing.
|
31828108 |
2019 |
Schizophrenia
|
0.320 |
Biomarker
|
disease |
PSYGENET |
We evaluated the PCQAP gene, which maps within the DGS/VCFS interval, as a potential candidate for schizophrenia susceptibility.
|
12497610 |
2003 |
Schizophrenia
|
0.320 |
Biomarker
|
disease |
PSYGENET |
These findings limit the role of exon 7 PCQAP polymorphisms in the pathogenesis of schizophrenia.
|
15318033 |
2004 |
Schizoaffective Disorder
|
0.300 |
Biomarker
|
disease |
PSYGENET |
Association study between CAG trinucleotide repeats in the PCQAP gene (PC2 glutamine/Q-rich-associated protein) and schizophrenia.
|
12497610 |
2003 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
To confirm these data on the protein level, we executed immunohistochemical (IHC) staining against MED15 on a tissue microarray containing 184 samples of the most common subtypes of the tumour at the various stages.
|
29400661 |
2018 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Moreover, the methylated TIG1 sequence was detected in 39 of 43 (90.7%) primary NPC tumors by MSP.
|
15455391 |
2005 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Genetic alterations of the mediator subunit 15 (MED15) in separate tumor entities have been described previously.
|
30127891 |
2018 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The expression of TIG1 is decreased in malignant prostate carcinoma or poorly differentiated colorectal adenocarcinoma, but TIG1 is present in benign or well-differentiated tumors.
|
27989102 |
2016 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Our data suggest that C/ebpalpha and Tig1 function as tumor suppressor proteins in endometrial cancers and that their reexpression may be a therapeutic target.
|
15886297 |
2005 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The tazarotene-induced gene 1 (TIG1) is a putative tumor suppressor gene.
|
22126303 |
2011 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The tazarotene-induced gene 1 (TIG1) protein is a retinoid-inducible growth regulator and is considered a tumor suppressor.
|
29902837 |
2018 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Retinoic Acid Receptor Responder (RARRES1)/ Tazarotene-induced gene-1 (TIG-1) is a putative tumor suppressor gene that exerts its tumor suppressor function via unknown mechanisms.
|
28678839 |
2017 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Tazarotene-induced gene 1 (TIG1) is a retinoid-inducible type II tumour suppressor gene.
|
21575264 |
2011 |
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Hypermethylation of CpG islands has been associated with silencing of various tumor suppressor genes, and the retinoid acid receptor beta (RARbeta), cellular retinol-binding protein 1 (CRBP1), and tazarotene-induced gene 1 (TIG1) genes have been associated with retinoic acid signaling.
|
16134180 |
2005 |
Malignant neoplasm of prostate
|
0.090 |
Biomarker
|
disease |
BEFREE |
We used a quantitative, methylation-specific PCR to analyze methylation patterns at five gene loci (APC, GSTP1, PTGS2, RARbeta and TIG1) in 84 prostate cancer (PCA) tissues (Gleason Score ≤7).
|
24324057 |
2013 |