Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.040 Biomarker group BEFREE Overexpressed FAL1 activated Akt pathway via interacting with PDK1 in EC cell lines. 30178844 2018
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.040 Biomarker group BEFREE 3-Phosphoinositide-dependent protein kinase-1 (PDK1) has been reported to be closely correlated with proliferation, apoptosis and invasion of esophageal cancer cells. 25416048 2014
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.040 AlteredExpression group BEFREE The current study was conducted to explore the inhibitory effects of a small interfering RNA (siRNA) on 3-phosphoinositide-dependent protein kinase 1 (PDK1) expression in esophageal cancer 9706 (EC9706) cells and the influence on their biological behavior. 23098536 2012
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.040 AlteredExpression group BEFREE Restoration of the miR-375 expression in esophageal cancer cell lines downregulated the PDK1 expression. 21533613 2011